PMID: 8940987Nov 1, 1996Paper

Experimental transmission of Powassan virus (Flaviviridae) by Ixodes scapularis ticks (Acari:Ixodidae)

The American Journal of Tropical Medicine and Hygiene
A Costero, M A Grayson

Abstract

Transmission experiments were performed with Ixodes scapularis ticks from an uninfected laboratory colony. Immature and adult ticks were exposed to Powassan (POW) viremic hamsters and rabbits, respectively. Oral infection rates for engorged larvae, nymphs and females fed on POW-infected hosts were 10%, 40%, and 57%, respectively. Transstadial transmission rates for nymphs exposed to POW virus as larvae, adults exposed as larvae, and adults exposed as nymphs, were 9.5%, 10%, and 54%, respectively. Evidence of transovarial transmission occurred when two uninfected hamsters, exposed to F2 larvae and nymphs originally exposed to POW virus in the F1 nymphal stage, seroconverted to POW virus with hemagglutination inhibition titers of 80 and 5,120, respectively; the transovarial transmission rate was 16.6%. All developmental stages were able to transmit virus orally to uninfected hosts regardless of when the ticks were originally exposed to the virus. These results suggest that I. scapularis is a competent vector of POW virus under experimental conditions.

Citations

Dec 8, 2005·CNS Drugs·Göran Günther, Mats Haglund
Aug 19, 2011·Journal of Medical Entomology·Jesse L BrunnerRichard S Ostfeld
Nov 29, 2014·Parasites & Vectors·Chantel N KrakowetzNeil B Chilton
Dec 14, 2018·Clinical Microbiology Reviews·Gábor Kemenesi, Krisztián Bányai
Dec 8, 2009·Annual Review of Entomology·Gregory D Ebel
Aug 15, 2012·The American Journal of Tropical Medicine and Hygiene·John F Anderson, Philip M Armstrong
Jun 21, 2019·The American Journal of Tropical Medicine and Hygiene·Rebecca M RobichRobert P Smith
Jul 20, 2019·Scientific Reports·Stephen SameroffChris Oura
May 23, 2020·Journal of Medical Entomology·Rebecca J Eisen, Christopher D Paddock
May 13, 2017·Vector Borne and Zoonotic Diseases·Meghan E Hermance, Saravanan Thangamani
Jan 7, 2017·Virus Evolution·Nathan D GrubaughDoug E Brackney
May 30, 2019·The New England Journal of Medicine·Ze-Dong WangQuan Liu
Jan 4, 2020·Clinical Microbiology Reviews·Susan Madison-AntenucciElizabeth Kauffman
Nov 22, 2002·The New England Journal of Medicine·Lois Gitlin WurzelDavid A Leiby
Nov 21, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marc Y El KhouryGary P Wormser
Apr 4, 2017·ILAR Journal·Rebecca J EisenChristopher D Paddock
Jun 19, 2018·Zoonoses and Public Health·Tricia CorrinLisa A Waddell
May 26, 2010·Journal of Medical Entomology·S B CohenA C Moncayo
Apr 24, 2020·Frontiers in Cellular and Infection Microbiology·Philip E Stewart, Marshall E Bloom
Oct 6, 2020·PLoS Neglected Tropical Diseases·Benjamin L KendallMarshall E Bloom
Apr 12, 2021·Wilderness & Environmental Medicine·David Della-GiustinaKatja Goldflam
Apr 23, 2021·Journal of Medical Entomology·Jean I TsaoGraham J Hickling
Feb 24, 2018·ACS Infectious Diseases·Jeffrey M GrabowskiMarshall E Bloom
Jul 29, 2008·Neurologic Clinics·Larry E DavisKenneth L Tyler

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.