Experimental validation of convection-diffusion discretisation scheme employed for computational modelling of biological mass transport.

Biomedical Engineering Online
Gráinne T CarrollM T Walsh

Abstract

The finite volume solver Fluent (Lebanon, NH, USA) is a computational fluid dynamics software employed to analyse biological mass-transport in the vasculature. A principal consideration for computational modelling of blood-side mass-transport is convection-diffusion discretisation scheme selection. Due to numerous discretisation schemes available when developing a mass-transport numerical model, the results obtained should either be validated against benchmark theoretical solutions or experimentally obtained results. An idealised aneurysm model was selected for the experimental and computational mass-transport analysis of species concentration due to its well-defined recirculation region within the aneurysmal sac, allowing species concentration to vary slowly with time. The experimental results were obtained from fluid samples extracted from a glass aneurysm model, using the direct spectrophometric concentration measurement technique. The computational analysis was conducted using the four convection-diffusion discretisation schemes available to the Fluent user, including the First-Order Upwind, the Power Law, the Second-Order Upwind and the Quadratic Upstream Interpolation for Convective Kinetics (QUICK) schemes. The fluid has...Continue Reading

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Citations

Nov 18, 2015·Annals of Biomedical Engineering·Eoin A MurphyFergal J Boyle
Apr 28, 2016·Biophysical Journal·Vijay GovindarajanAlexander Y Mitrophanov
Mar 1, 2018·Biophysical Journal·Vijay GovindarajanAlexander Y Mitrophanov

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Software Mentioned

CFDS
FV
CFX
ADINA
Flow3D
Gambit
FV Fluent
Fluent

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