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Exploiting evolutionary non-commutativity to prevent the emergence of bacterial antibiotic resistance

bioRxiv

Jul 29, 2014

Daniel NicholJacob Scott

Abstract

The increasing rate of antibiotic resistance and slowing discovery of novel antibiotic treatments presents a growing threat to public health. Here, we develop a Markov Chain model of evolution in asexually reproducing populations which is an encoding of the Strong Selection Weak Mutatio...read more

Mentioned in this Paper

Resistance Process
Anatomical Space Structure
Mutation Abnormality
Species
Monobactams
Antibiotics
Superficial Cervical Lymphatic Chain
Antibiotic Therapy
Study
Targeted Therapy
30
5
Paper Details
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Exploiting evolutionary non-commutativity to prevent the emergence of bacterial antibiotic resistance

bioRxiv

Jul 29, 2014

Daniel NicholJacob Scott

PMID: 990007542

DOI: 10.1101/007542

Abstract

The increasing rate of antibiotic resistance and slowing discovery of novel antibiotic treatments presents a growing threat to public health. Here, we develop a Markov Chain model of evolution in asexually reproducing populations which is an encoding of the Strong Selection Weak Mutatio...read more

Mentioned in this Paper

Resistance Process
Anatomical Space Structure
Mutation Abnormality
Species
Monobactams
Antibiotics
Superficial Cervical Lymphatic Chain
Antibiotic Therapy
Study
Targeted Therapy
30
5
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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    No citations available

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