Exploiting host compensatory responses: the 'must' of manipulation?

Trends in Parasitology
Thierry LefèvreFrédéric Thomas

Abstract

Parasite-induced alterations of the host phenotype have been reported in many systems. These changes are traditionally categorized into three kinds of phenomena: secondary outcomes of infection with no adaptive value, host adaptations that reduce the detrimental consequences of infection and parasitic adaptations that facilitate transmission. However, this categorization is a simple view, and host modifications should be considered as co-evolved traits, rather than a total takeover. Here, we present a novel scenario of manipulation, which has considerable potential to resolve issues that are specific to the evolution of behavioural alterations induced by parasites. It is proposed that certain parasites affect fitness-related traits in their hosts to trigger host compensatory responses because these responses can meet the transmission objectives of parasites.

References

Mar 1, 1986·The American Journal of Tropical Medicine and Hygiene·P A RossignolA Spielman
Jun 1, 1982·Journal of Clinical Pathology·D N Challacombe, P D Dawkins
Jan 1, 1981·Transactions of the Royal Society of Tropical Medicine and Hygiene·D H Molyneux, L Jenni
Jan 1, 1999·Proceedings. Biological Sciences·M Polak, W T Starmer
Apr 13, 2001·Trends in Ecology & Evolution·N B. Metcalfe, P Monaghan
Nov 1, 2001·Trends in Parasitology·H Hurd
Jan 5, 2002·Parasitology·R E Sorensen, D J Minchella
Nov 5, 2002·Annual Review of Entomology·Hilary Hurd
Mar 29, 2005·Behavioural Processes·Todd Wellnitz
Jan 13, 2006·Behavioural Processes·Fleur PontonFrédéric Thomas
Mar 16, 2007·Proceedings of the National Academy of Sciences of the United States of America·Jeffrey P Hoover, Scott K Robinson
Jun 26, 2007·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Thierry Lefèvre, Frédéric Thomas
Jul 3, 2007·PLoS Pathogens·Matthew E Rogers, Paul A Bates

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Citations

Aug 22, 2014·Proceedings. Biological Sciences·Clayton E CresslerEdward McCauley
May 25, 2011·Proceedings of the National Academy of Sciences of the United States of America·Candice A StaffordDiane E Ullman
Feb 6, 2016·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Tazzio TissotFrédéric Thomas
Jun 8, 2013·Molecular Ecology·Stineke van HouteMonique M van Oers
Mar 2, 2016·Parasites & Vectors·Johanna R OhmLauren J Cator
Nov 30, 2013·The Journal of Animal Ecology·Fabrice LalubinPhilippe Christe
Oct 7, 2015·Trends in Parasitology·Robert Poulin, Fanny Maure
Apr 17, 2010·Evolution; International Journal of Organic Evolution·Nathalie FranceschiThierry Rigaud
Jun 23, 2009·Acta Tropica·Romanico B G Arrighi, Ingrid Faye
Sep 5, 2015·Parasitology Research·Luz Garcia-LongoriaAlfonso Marzal
Mar 24, 2016·Behavioral Ecology : Official Journal of the International Society for Behavioral Ecology·Nina Hafer, Manfred Milinski
Nov 11, 2014·The Journal of Animal Ecology·Aabir BanerjiOliver Kaltz
Jan 9, 2010·Trends in Parasitology·Anna CohuetDidier Fontenille
Aug 18, 2017·The Journal of Experimental Biology·Melissa A Bernardo, Michael S Singer
Feb 4, 2010·Expert Review of Proteomics·Philippe HolzmullerDavid Georges Biron
Sep 9, 2011·Memórias do Instituto Oswaldo Cruz·Erika Martins BragaGediminas Valkiūnas
Jan 1, 2012·Insects·Jacobus C de Roode, Thierry Lefèvre
Dec 12, 2012·The Journal of Experimental Biology·Robert Poulin
Dec 12, 2012·The Journal of Experimental Biology·Fanny MaureFrédéric Thomas
Dec 12, 2012·The Journal of Experimental Biology·Fanny MaureFrédéric Thomas

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