PMID: 3320903Nov 1, 1987Paper

Exploration of endogenous mechanisms controlling the inflammatory reaction, by the study of counter-irritation: release of prostaglandins, formation of kinins and accumulation of leukocytes

Pathologie-biologie
J Damas, E Deflandre

Abstract

This review was focused on counter irritation by turpentine in the rat. The involvement of sympathetic system, adrenal steroids, beta-endorphin, axon reflexes, haptoglobin, alpha-2-macroglobulin, complement activation, prostaglandin synthesis, kinin formation and leukocyte accumulation was considered as possible explanation of the anti-inflammatory effect of counter irritation by turpentine. The main mechanism consists of the reduction of leucocyte accumulation.

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