Exploration of the DPP-4 inhibitors with a focus on saxagliptin

Expert Opinion on Pharmacotherapy
Jay H ShubrookFrank L Schwartz

Abstract

Type 2 diabetes (T2DM) has become a worldwide epidemic. Despite a vast array of new compounds to treat T2DM, recommended treatment goals are consistently not achieved in this country thus suggesting a need to increase treatment options. To review the role of DPP-4 inhibitors in treatment of T2DM with an emphasis on saxagliptin. The authors discuss the role of this new class of medications in treatment of T2DM, review the current available studies and the unique characteristics of saxagliptin. Saxagliptin, a DPP-4 inhibitor, is one of an important new class of compounds, which seems to be particularly safe and effective especially in early treatment of T2DM.

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Citations

Feb 13, 2014·Journal of Labelled Compounds & Radiopharmaceuticals·Scott B TranSamuel J Bonacorsi
Sep 10, 2015·Biomedit︠s︡inskai︠a︡ khimii︠a︡·A A Spasov, N I Chepljaeva

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