Exploration of the protein requirement during weight loss in obese older adults

Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition
Peter J M Weijs, Robert R Wolfe

Abstract

Currently there is no consensus on protein requirements for obese older adults during weight loss. Here we explore the potential use of a new method for assessment of protein requirements based on changes in appendicular muscle mass during weight loss. 60 obese older adults were subjected to 13 wk weight loss program, including hypocaloric diet and resistance training. Assessment of appendicular muscle mass was performed by DXA at baseline and after 13 wk challenge period, and the difference calculated as muscle mass change. Protein intake (g/kg body weight and g/kg fat free mass (FFM)) at 13wks was used as marker of protein intake during 13 wk period. 30 subjects received 10 times weekly 20 g protein supplement throughout the 13 week hypocaloric phase which is included in the calculation of total protein intake. Receiver operating characteristic (ROC) curve analysis was used to explore the optimal cutoff point for protein intake (g/kg) versus increase in appendicular muscle mass of more than 250 g over 13 wks (y/n). Subsequently, logistic regression analysis was performed for protein intake cutoff and muscle mass accretion, adjusted for sex, age, baseline BMI, and training compliance. ROC curve analysis provided a protein inta...Continue Reading

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Citations

Apr 27, 2017·Journal of Cachexia, Sarcopenia and Muscle·Lidia SantarpiaFabrizio Pasanisi
Apr 8, 2017·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Peter J M WeijsStephen A McClave
Apr 17, 2018·Advances in Nutrition·Connie W Bales, Kathryn N Porter Starr
Jul 28, 2019·Nutrients·David D ChurchArny A Ferrando
Dec 12, 2019·Heart Failure Reviews·Vittorio Emanuele Bianchi

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