Exploring (57)Co as a new isotope for brachytherapy applications

Medical Physics
Shirin A EngerLuc Beaulieu

Abstract

The characteristics of the radionuclide (57)Co make it interesting for use as a brachytherapy source. (57)Co combines a possible high specific activity with the emission of relatively low-energy photons and a half-life (272 days) suitable for regular source exchanges in an afterloader. (57)Co decays by electron capture to the stable (57)Fe with emission of 136 and 122 keV photons. A hypothetical (57)Co source based on the Flexisource brachytherapy encapsulation with the active core set as a pure cobalt cylinder (length 3.5 mm and diameter 0.6 mm) covered with a cylindrical stainless-steel capsule (length 5 mm and thickness 0.125 mm) was simulated using Geant4 Monte Carlo (MC) code version 9.4. The radial dose function, g(r), and anisotropy function F(r,θ), for the line source approximation were calculated following the TG-43U1 formalism. The results were compared to well-known (192)Ir and (125)I radionuclides, representing the higher and the lower energy end of brachytherapy, respectively. The mean energy of photons in water, after passing through the core and the encapsulation material was 123 keV. This hypothetical (57)Co source has an increasing g(r) due to multiple scatter of low-energy photons, which results in a more unif...Continue Reading

References

Oct 5, 2001·Medical Physics·D BaltasN Zamboglou
Aug 13, 2004·Medical Physics·J Pérez-CalatayudF Ballester
Jul 15, 2005·Medical Physics·Emily Poon, Frank Verhaegen
Feb 7, 2007·Medical Physics·D GraneroJ Venselaar
May 7, 2010·Medical Physics·Facundo BallesterMark J Rivard
Oct 14, 2011·Medical Physics·Shirin A EngerLuc Beaulieu

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Citations

May 3, 2014·Medical Physics·Quentin E AdamsRyan T Flynn
Feb 24, 2016·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Mahdi Ghorbani, Marziyeh Behmadi
Mar 8, 2017·Radiology and Oncology·Mahdi GhorbaniRamin Shahraini
Jan 24, 2013·Physics in Medicine and Biology·Shirin A EngerRyan T Flynn

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