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Exploring data from genetic association studies using Bayesian variable selection and the Dirichlet process: application to searching for gene × gene patterns

Genetic Epidemiology

Aug 2, 2012

Michail PapathomasSylvia Richardson

Abstract

We construct data exploration tools for recognizing important covariate patterns associated with a phenotype, with particular focus on searching for association with gene-gene patterns. To this end, we propose a new variable selection procedure that employs latent selection weights and ...read more

Mentioned in this Paper

Genome-Wide Association Study
In Silico
Genetic Association Studies
Candidate Gene Identification
Tandem
Epidemiology
Two-Parameter Models
Bayesian Prediction
Genetic Predisposition to Disease
Single Nucleotide Polymorphism
1
39
Paper Details
References
  • References17
  • Citations10
12
  • References17
  • Citations10
1

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Exploring data from genetic association studies using Bayesian variable selection and the Dirichlet process: application to searching for gene × gene patterns

Genetic Epidemiology

Aug 2, 2012

Michail PapathomasSylvia Richardson

PMID: 22851500

DOI: 10.1002/gepi.21661

Abstract

We construct data exploration tools for recognizing important covariate patterns associated with a phenotype, with particular focus on searching for association with gene-gene patterns. To this end, we propose a new variable selection procedure that employs latent selection weights and ...read more

Mentioned in this Paper

Genome-Wide Association Study
In Silico
Genetic Association Studies
Candidate Gene Identification
Tandem
Epidemiology
Two-Parameter Models
Bayesian Prediction
Genetic Predisposition to Disease
Single Nucleotide Polymorphism
1
39

Similar Papers Found In These Feeds

Department of Paediatrics - U. Cambridge

The University Department of Paediatrics is part of the School of Clinical Medicine, at the University of Cambridge, and is located on the Addenbrooke’s Hospital site. The Department of Paediatrics is involved in teaching, research and clinical practice and is an internationally recognised centre for research in child health and development. Here is the latest research on researchers in the Department of Paediatrics at the University of Cambridge.

Related Papers

Biometrics

A spatial dirichlet process mixture model for clustering population genetics data

BiometricsSeptember 10, 2010
Brian J Reich, Howard D Bondell
Paper Details
References
  • References17
  • Citations10
12
  • References17
  • Citations10
1
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