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Exploring DNA structures in real-time polymerase kinetics using Pacific Biosciences sequencer data

bioRxiv

Dec 2, 2013

Sterling SawayaNeil John Gemmell

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Abstract

Pausing of DNA polymerase can indicate the presence of a DNA structure that differs from the canonical double-helix. Here we detail a method to investigate how polymerase pausing in the Pacific Biosciences sequencer reads can be related to DNA structure. The Pacific Biosciences sequence...read more

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DNA Sequence
Carrageenan
Helix (Snails)
Research Personnel
G-Quadruplexes
DNA, Z-Form
Patterns
G-Quadruplexes, DNA
Structure
Protein Helix
6
6
Paper Details
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  • Exploring DNA structures in real-time polymerase kinetics using Pacific Biosciences sequencer data

    bioRxiv

    Dec 2, 2013

    Sterling SawayaNeil John Gemmell

    PMID: 990001024

    DOI: 10.1101/001024

    Abstract

    Pausing of DNA polymerase can indicate the presence of a DNA structure that differs from the canonical double-helix. Here we detail a method to investigate how polymerase pausing in the Pacific Biosciences sequencer reads can be related to DNA structure. The Pacific Biosciences sequence...read more

    Mentioned in this Paper

    DNA Sequence
    Carrageenan
    Helix (Snails)
    Research Personnel
    G-Quadruplexes
    6
    6
    Paper Details
    References
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