Exploring Massive Incomplete Lineage Sorting in Arctoids (Laurasiatheria, Carnivora)

Molecular Biology and Evolution
Liliya DoroninaJürgen Schmitz

Abstract

Freed from the competition of large raptors, Paleocene carnivores could expand their newly acquired habitats in search of prey. Such changing conditions might have led to their successful distribution and rapid radiation. Today, molecular evolutionary biologists are faced, however, with the consequences of such accelerated adaptive radiations, because they led to sequential speciation more rapidly than phylogenetic markers could be fixed. The repercussions being that current genealogies based on such markers are incongruent with species trees.Our aim was to explore such conflicting phylogenetic zones of evolution during the early arctoid radiation, especially to distinguish diagnostic from misleading phylogenetic signals, and to examine other carnivore-related speciation events. We applied a combination of high-throughput computational strategies to screen carnivore and related genomes in silico for randomly inserted retroposed elements that we then used to identify inconsistent phylogenetic patterns in the Arctoidea group, which is well known for phylogenetic discordances.Our combined retrophylogenomic and in vitro wet lab approach detected hundreds of carnivore-specific insertions, many of them confirming well-established spl...Continue Reading

References

Jan 1, 1995·Mammalian Genome : Official Journal of the International Mammalian Genome Society·H H van der Vlugt, J A Lenstra
Mar 1, 1994·Molecular Phylogenetics and Evolution·P B VranaW C Wheeler
Mar 4, 1997·Proceedings of the National Academy of Sciences of the United States of America·J Jurka
Jul 21, 1998·Molecular Phylogenetics and Evolution·J J Flynn, M A Nedbal
Feb 2, 2000·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·A M Shedlock, N Okada
Apr 26, 2000·Molecular Biology and Evolution·J P SlatteryS J O'Brien
Feb 24, 2001·Nature·W J MurphyS J O'Brien
Nov 15, 2001·Mammalian Genome : Official Journal of the International Mammalian Genome Society·M NikaidoN Okada
May 30, 2002·Proceedings of the National Academy of Sciences of the United States of America·Ulfur ArnasonAxel Janke
Jul 9, 2002·Molecular Phylogenetics and Evolution·Mark P Simmons, John V Freudenstein
Jul 25, 2003·Molecular Phylogenetics and Evolution·Heather Amrine-MadsenMark S Springer
Sep 23, 2003·Proceedings of the National Academy of Sciences of the United States of America·W James KentDavid Haussler
Jun 3, 2005·Molecular Biology and Evolution·Hidenori NishiharaNorihiro Okada
Jun 21, 2005·Molecular Phylogenetics and Evolution·Isabelle Delisle, Curtis Strobeck
Oct 26, 2005·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Li Yu, Ya-Ping Zhang
Dec 13, 2005·Genome Research·Wei Wang, Ewen F Kirkness
Mar 7, 2006·PLoS Biology·Jan Ole KriegsJürgen Schmitz
Apr 1, 2006·Cytogenetic and Genome Research·D Solter
May 17, 2006·Trends in Ecology & Evolution·Andrew M ShedlockNorihiro Okada
Jun 10, 2006·Trends in Ecology & Evolution·Jeffrey L Boore
Jul 20, 2006·Genetica·Li Yu, Ya-ping Zhang
Nov 15, 2006·Molecular Phylogenetics and Evolution·Conrad A MattheeTerence J Robinson
Feb 16, 2007·Trends in Ecology & Evolution·James B Whitfield, Peter J Lockhart
Mar 10, 2007·Systematic Biology·David A RayMark A Batzer
Oct 9, 2007·Molecular Phylogenetics and Evolution·Ulfur ArnasonMorgan Kullberg
Jun 24, 2008·Systematic Biology·John C Avise, Terence J Robinson
Mar 6, 2009·Genome Research·Gennady ChurakovJürgen Schmitz
Aug 25, 2009·Molecular Phylogenetics and Evolution·Jun J SatoHitoshi Suzuki
Nov 11, 2009·Molecular Phylogenetics and Evolution·Ingi AgnarssonLaura J May-Collado
Jan 27, 2010·Molecular Biology and Evolution·Gennady ChurakovJürgen Schmitz
Feb 9, 2010·Molecular Phylogenetics and Evolution·Eduardo EizirikStephen J O'Brien
Jul 30, 2010·PLoS Biology·Maria A NilssonJürgen Schmitz
Aug 25, 2011·Nature Communications·Alexander SuhJürgen Schmitz

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Citations

Mar 17, 2017·Genome Research·Liliya DoroninaJürgen Schmitz
Dec 3, 2017·Scientific Reports·William G DodtMaria A Nilsson
Jul 31, 2020·Genome Research·Gennady ChurakovJürgen Schmitz

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