Exploring phenotypic data at the rat genome database

Current Protocols in Bioinformatics
S TwiggerSusan Bromberg

Abstract

The laboratory rat, Rattus norvegicus, is an important model of human health and disease, and experimental findings in the rat have direct relevance to human-based research. The Rat Genome Database (RGD, http://rgd.mcw.edu) is a model-organism database that provides access to wide variety of curated rat data such as genes and their homologs, quantitative trait loci, phenotypes, comparative mapping, and genome analysis. We present an overview of the database followed by specific examples that can be used to gain experience in employing RGD to explore the wealth of functional data available for the rat. We show how to make associations with the genome and use comparative tools to link the rat with human and mouse in order to integrate results from these three species of critical biomedical importance.

References

Oct 9, 2002·Genome Research·Lincoln D SteinSuzanna Lewis
Apr 2, 2004·Nature·Richard A GibbsUNKNOWN Rat Genome Sequencing Project Consortium
Dec 21, 2004·Nucleic Acids Research·Norberto de la CruzHoward Jacob
Aug 18, 2005·Physiological Genomics·Simon N TwiggerHoward J Jacob

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Citations

Feb 26, 2013·Briefings in Bioinformatics·Stanley J F LaulederkindHoward J Jacob
Jul 16, 2010·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Xiaoguang ChenJi Ma
May 23, 2007·Pigment Cell Research·Fabien MurisierFriedrich Beermann
Sep 29, 2015·Scientific Reports·Mi LiuTaijiao Jiang
Oct 17, 2009·Journal of Biomedicine & Biotechnology·Raja Loganantharaj, Jun Chung
Mar 8, 2012·Cellular & Molecular Biology Letters·Cunshuan XuGaiping Wang
Jan 26, 2011·Cellular and Molecular Neurobiology·Cunshuan XuAiling Lu

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