Exploring racial differences in IgE-mediated food allergy in the WHEALS birth cohort

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Christine L M JosephChristine Cole Johnson

Abstract

Suspected food allergies are the cause of more than 200,000 visits to the emergency department annually. Racial differences in the prevalence of food allergy have also been reported, but the evidence is less conclusive. Researchers continue to struggle with the identification of food allergy for epidemiologic studies. To explore racial differences in IgE-mediated food allergy (IgE-FA) in a birth cohort. We used a panel of board-certified allergists to systematically identify IgE-FA to egg, milk, or peanut in a multiethnic birth cohort in which patient medical history, patient symptoms, and clinical data were available through 36 months of age. Of the 590 infants analyzed, 52.9% were male and 65.8% African American. Sensitization (serum specific IgE >0.35 IU/mL) to the food allergens was significantly higher for African American children compared with non-African American children as has been previously reported. No statistically significant racial/ethnic differences in IgE-FA were observed; however, a higher proportion of African American children were designated as having peanut allergy, and the percentage of African American children with an IgE level greater than 95% predictive decision points for peanut was 1.7% vs 0.5% for...Continue Reading

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Citations

Apr 10, 2016·The Journal of Allergy and Clinical Immunology·George du ToitGideon Lack
Feb 19, 2020·Current Allergy and Asthma Reports·Christopher M WarrenRuchi S Gupta
May 15, 2019·Nutrients·Julie D Flom, Scott H Sicherer
Jan 16, 2019·JAMA Network Open·Ruchi S GuptaKari C Nadeau
Jul 11, 2020·The Journal of Allergy and Clinical Immunology·Stanislaw J GabryszewskiDavid A Hill
Oct 17, 2020·The Journal of Allergy and Clinical Immunology. in Practice·Christopher M WarrenRuchi S Gupta
Jan 18, 2020·The Journal of Allergy and Clinical Immunology. in Practice·Bruce G Bender
Apr 18, 2021·Immunology and Allergy Clinics of North America·Christopher M WarrenRuchi S Gupta
Jul 19, 2021·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Ann E ClarkeMoshe Ben-Shoshan
Jul 12, 2021·The Journal of Allergy and Clinical Immunology. in Practice·Carla M Davis

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