Exploring the Dual Interaction of Natural Rhamnolipids with Plant and Fungal Biomimetic Plasma Membranes through Biophysical Studies

International Journal of Molecular Sciences
Noadya MonnierCatherine Sarazin

Abstract

Rhamnolipids (RLs) are potential biocontrol agents for crop culture protection. Their mode of action has been proposed as dual, combining plant protection activation and antifungal activities. The present work focuses on the interaction of natural RLs with plant and fungi membrane models at the molecular scale. Representative models were constructed and the interaction with RLs was studied by Fourier transform infrared (FTIR) and deuterium nuclear magnetic resonance (²H NMR) spectroscopic measurements. Molecular dynamic (MD) simulations were performed to investigate RL insertion in lipid bilayers. Our results showed that the RLs fit into the membrane models and were located near the lipid phosphate group of the phospholipid bilayers, nearby phospholipid glycerol backbones. The results obtained with plant plasma membrane models suggest that the insertion of RLs inside the lipid bilayer did not significantly affect lipid dynamics. Oppositely, a clear fluidity increase of fungi membrane models was observed. This effect was related to the presence and the specific structure of ergosterol. The nature of the phytosterols could also influence the RL effect on plant plasma membrane destabilization. Subtle changes in lipid dynamics coul...Continue Reading

References

Jan 19, 1979·Biochimica Et Biophysica Acta·J H DavisD V Godin
Jan 1, 1986·Faraday Discussions of the Chemical Society·F M Goñi, J L Arrondo
Mar 21, 1983·Biochimica Et Biophysica Acta·J H Davis
Feb 1, 1996·Journal of Molecular Graphics·W HumphreyK Schulten
May 13, 1999·Biochimica Et Biophysica Acta·A GrauA Ortiz
Mar 15, 2006·The Plant Cell·Tomomi MorikawaDaisaku Ohta
Jul 29, 2006·International Journal of Pharmaceutics·Antonio OrtizFrancisco J Aranda
Jan 11, 2007·The Journal of Chemical Physics·Giovanni BussiMichele Parrinello
Jan 25, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Francisco J ArandaAntonio Ortiz
Feb 24, 2007·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Johannes G BeckErick J Dufourc
Sep 13, 2007·Journal of Computational Chemistry·Karl N KirschnerRobert J Woods
Jun 28, 2008·Applied Biochemistry and Biotechnology·Ahmad Mohammad Abdel-MawgoudNadia Abdel-Haleem Hassouna
Oct 9, 2008·Journal of the American Chemical Society·Tim BartelsMichael F Brown
Nov 22, 2008·Plant, Cell & Environment·Anne-Lise VarnierStephan Dorey
Jul 8, 2009·Chemistry and Physics of Lipids·Marina SánchezAntonio Ortiz
Oct 20, 2009·Journal of Colloid and Interface Science·Marina SánchezAntonio Ortiz
Mar 26, 2010·Applied Microbiology and Biotechnology·Ahmad Mohammad Abdel-MawgoudEric Déziel
Sep 8, 2010·Chembiochem : a European Journal of Chemical Biology·Sonia RippaLaure Béven
Oct 12, 2010·Chemistry and Physics of Lipids·Marina SánchezAntonio Ortiz
Apr 19, 2011·Journal of Computational Chemistry·Naveen Michaud-AgrawalOliver Beckstein
Jan 1, 2010·International Journal of Molecular Sciences·Parul VatsaStephan Dorey
Feb 23, 2012·The Journal of Physical Chemistry. B·Joakim P M Jämbeck, Alexander P Lyubartsev
Jun 21, 2012·Biophysical Journal·James A SvetlovicsPaulo F Almeida
Feb 15, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Hui WangJeanne E Pemberton

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Citations

Jul 12, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mathilde RobineauEssaid Ait Barka
Oct 18, 2019·Frontiers in Plant Science·Marie-Claire HéloirBenoit Poinssot
Jul 30, 2019·Molecular Plant Pathology·Romain SchellenbergerStéphan Dorey
Oct 6, 2020·Frontiers in Bioengineering and Biotechnology·Jérôme CrouzetStéphan Dorey
Dec 31, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rémi PlatelAli Siah
Jun 26, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Meryem BelkilaniCarole Chaix
Sep 26, 2021·Proceedings of the National Academy of Sciences of the United States of America·Romain SchellenbergerStéphan Dorey
Aug 5, 2020·Biochimica Et Biophysica Acta. Biomembranes·Marius HerzogRoland Winter
Dec 2, 2021·Journal of Experimental Botany·Sylvain CordelierSandrine Dhondt-Cordelier

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Methods Mentioned

BETA
isothermal titration calorimetry
infrared spectroscopy
nuclear magnetic resonance
NMR
light scattering

Software Mentioned

Maestro
LINear Constraint Solver ( LINCS )
Automated Topology Builder
GLYCAM06
GROMACS
MDAnalysis
AMBER ff99SB - ILDN
multisca

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