Exploring the limit of metazoan thermal tolerance via comparative proteomics: thermally induced changes in protein abundance by two hydrothermal vent polychaetes.

Proceedings. Biological Sciences
Geoffrey F DillyPeter R Girguis

Abstract

Temperatures around hydrothermal vents are highly variable, ranging from near freezing up to 300°C. Nevertheless, animals thrive around vents, some of which live near the known limits of animal thermotolerance. Paralvinella sulfincola, an extremely thermotolerant vent polychaete, and Paralvinella palmiformis, a cooler-adapted congener, are found along the Juan de Fuca Ridge in the northwestern Pacific. We conducted shipboard high-pressure thermotolerance experiments on both species to characterize the physiological adaptations underlying P. sulfincola's pronounced thermotolerance. Quantitative proteomics, expressed sequence tag (EST) libraries and glutathione assays revealed that P. sulfincola (i) exhibited an upregulation in the synthesis and recycling of glutathione with increasing temperature, (ii) downregulated nicotinamide adenine dinucleotide (NADH) and succinate dehydrogenases (key enzymes in oxidative phosphorylation) with increasing temperature, and (iii) maintained elevated levels of heat shock proteins (HSPs) across all treatments. In contrast, P. palmiformis exhibited more typical responses to increasing temperatures (e.g. increasing HSPs at higher temperatures). These data reveal differences in how a mesotolerant a...Continue Reading

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Citations

Sep 5, 2012·Integrative and Comparative Biology·Lars Tomanek
Oct 4, 2015·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Ikumi Nakamura-KusakabeKoji Inoue
Mar 5, 2015·Heredity·D PorcelliR R Snook
Nov 4, 2017·The Journal of Experimental Biology·Brent L LockwoodKristi L Montooth
Jul 8, 2016·The Journal of Experimental Biology·Matti Vornanen
Feb 14, 2019·Cell Stress & Chaperones·Serena CarraRobert M Tanguay
Jun 19, 2015·The Journal of Experimental Biology·Brent L LockwoodAndrew Y Gracey
Jun 19, 2015·The Journal of Experimental Biology·Lars Tomanek
Jun 3, 2021·International Journal of Molecular Sciences·Kazunori Watanabe, Takashi Ohtsuki

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