Exploring the predictive power of the unspecific risk category of the Basel Screening Instrument for Psychosis

Early Intervention in Psychiatry
David PeraltaAnita Riecher-Rössler

Abstract

Ultrahigh risk (UHR) criteria, consisting of brief limited intermittent psychotic symptoms (BLIPS), attenuated psychotic symptoms (APS) and genetic risk and deterioration (GRD) syndrome are the most widely used criteria for assessing the clinical high-risk state for psychosis (CHR-P). The Basel Screening Instrument for Psychosis (BSIP) includes a further risk category, the unspecific risk category (URC). However, little is known about the predictive power of this risk category compared to other risk categories. Two hundred CHR-P patients were detected as part of the Früherkennung von Psychosen (FePsy) study using the BSIP. Transition to psychosis was assessed in regular intervals for up to 7 years. Patients meeting only the URC criterion (n = 40) had a significantly lower risk of transition to psychosis than the UHR group (including BLIPS, APS and GRD) (HR 0.19 [0.05; 0.80] (P = 0.024). Furthermore, the URC only risk group had a lower transition risk than the APS without BLIPS group (P = 0.015) and a trendwise lower risk than the BLIPS group (P = 0.066). However, despite the lower transition risk in the URC only group, there were still two patients (5%) in this group with a later transition to psychosis. The URC includes patien...Continue Reading

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Citations

Feb 19, 2020·Molecular Psychiatry·Christina Andreou, Stefan Borgwardt
Oct 28, 2019·Social Psychiatry and Psychiatric Epidemiology·Letizia LeanzaAnita Riecher-Rössler
Sep 13, 2019·European Psychiatry : the Journal of the Association of European Psychiatrists·Katharina BeckAnita Riecher-Rössler
Aug 26, 2020·Translational Psychiatry·Renate de BockChristina Andreou
Sep 20, 2020·Journal of Psychiatric Research·Erich StuderusAnita Riecher-Rössler

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