Exposure Assessment to Mycotoxins in a Portuguese Fresh Bread Dough Company by Using a Multi-Biomarker Approach

Toxins
Susana ViegasC Viegas

Abstract

Mycotoxins are toxic mold metabolites that can persist in environment long after the fungi species responsible for their production disappear. Critical workplace for mycotoxins presence has already been studied and nowadays it is possible to recognize that exposure to mycotoxins through inhalation occurs due to their presence in dust. This study aimed to assess occupational co-exposure to multiple mycotoxins in a fresh bread dough company, an occupational setting not studied until now. Occupational exposure assessment to mycotoxins was done using a LC-MS/MS urinary multi-biomarker approach. Twenty-one workers and nineteen individuals that were used as controls participated in the study. Workers/controls (spot-urine) and environment (settled dust) samples were collected and analyzed. Concerning workers group, DON-GlcA, and OTA were the most prevalent biomarkers (>LOD), 66% and 90.5%, respectively. In the control group, OTA was also one of the most detected (68%) followed by CIT (58%) and DON-GlcA (58%). DON was the mycotoxin measured in high amounts in the settled dust sample (58.2 ng/g). Both workers and controls are exposed to several mycotoxins simultaneously. The workers group, due to their high contact with flour dust, reve...Continue Reading

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Citations

Jan 19, 2020·Microorganisms·Carla ViegasAnn Marie Coggins
Jul 1, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Liliana SilvaCeleste Lino
Mar 15, 2020·Toxins·Ricardo Assunção, Susana Viegas
Jun 27, 2019·International Journal of Environmental Health Research·Carla ViegasSusana Viegas
Feb 7, 2021·Toxins·Kristina HabschiedKrešimir Mastanjević
Jan 14, 2021·Environmental Research·Carla ViegasSusana Viegas
Apr 6, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·María IzcoLydia Alvarez-Erviti
Jun 2, 2021·Journal of Agricultural and Food Chemistry·Alfonso NarváezAlberto Ritieni
Mar 31, 2019·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Larissa T FrancoCarlos A F Oliveira

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