Exposure of dioxin-like chemicals in participants of the Anniston community health survey follow-up

The Science of the Total Environment
Eric YangLinda Birnbaum

Abstract

The 2014 follow-up of the Anniston Community Health Survey (ACHS II) consisted of 338 surviving participants from the 2005-2007 baseline study (ACHS) who had previous polychlorinated biphenyl (PCB) measurements, were not pregnant, and were not institutionalized. Questionnaires and blood samples provided the demographic, personal history, and chemical concentration data of the Anniston residents. Approximately 51% of participants were African American, 72% were female, and the mean age was 63 years old. The objectives of this study were to provide an exposure assessment of dioxin-like chemicals in the ACHS II participants and compare the measurements with the general United States (U.S.) population via the National Health and Nutrition Examination Survey (NHANES). Stratified analyses revealed significantly higher average total dioxin toxic equivalencies (TEQs) among African Americans compared to Whites (33.1 vs. 19.2 pg/g lipid), and in females compared to males (29.8 vs. 17.0 pg/g lipid). When adjusting for age, sex, and race in linear regression, we found ACHS II participants to have significantly higher total dioxin TEQ than the general 2014 U.S. population that we estimated for using half-life and NHANES 2003/04 data (most r...Continue Reading

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May 20, 2015·Environmental Science and Pollution Research International·Linda S BirnbaumM Pavuk

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Citations

Oct 15, 2019·Epigenetics : Official Journal of the DNA Methylation Society·Gary S PittmanDouglas A Bell
Jul 7, 2020·The Science of the Total Environment·Gary S PittmanDouglas A Bell
Oct 17, 2020·Toxicological Sciences : an Official Journal of the Society of Toxicology·Neelakanteswar Aluru, Sibel I Karchner
Apr 8, 2020·Chemical Research in Toxicology·Mele N AvillaChristopher A Bradfield

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