Exposure of motor vehicle examiners to carbon monoxide: a historical prospective mortality study

Archives of Environmental Health
F SternR A Curtis

Abstract

The National Institute for Occupational Safety and Health (NIOSH) investigated the health effects of chronic exposure to low concentrations of carbon monoxide by conducting a historical prospective cohort study of mortality patterns among 1,558 white male motor vehicle examiners who were employed in New Jersey for a minimum of 6 months between 1944 and 1973. Industrial hygiene surveys indicated that the examiners were exposed to carbon monoxide at a time-weighted average (TWA) of 10-24 ppm; the exposure level recommended by NIOSH is 35 ppm TWA. A modified life table technique was used to calculate cause-specific expected deaths for the cohort adjusted for age and calendar time periods. The expected deaths were compared to the number of observed deaths through August 1973. The cohort demonstrated a slight overall increase in cardiovascular disease deaths (124 observed vs. 118.4 expected), but a more pronounced excess was observed within the first 10 yr. following employment (28 observed vs. 20.9 expected). A statistically significant excess of cancer mortality was found for motor vehicle examiners after 30 yr latency (13 observed vs. 6.9 expected, P < 0.5); this excess, however, was not confined to any particular organ site. The...Continue Reading

References

Nov 1, 1976·Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association·T D Sterling, J J Weinkam
Mar 1, 1976·Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association·A J McMichael
Jan 1, 1971·Archives of Environmental Health·S I CohenS Permutt
Nov 1, 1972·Annals of Internal Medicine·W S AronowB Imparato
Jun 15, 1968·Experientia·S S Epstein, N Mantel
Sep 1, 1973·Annals of Internal Medicine·W S Aronow, M W Isbell
Feb 1, 1970·Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association·A D Hosey
Dec 1, 1958·Journal of Chronic Diseases·S J CUTLER, F EDERER
Nov 1, 1963·Archives of Environmental Health·J H SCHULTE

❮ Previous
Next ❯

Citations

Oct 17, 2009·Annals of Biomedical Engineering·Kinnera ErupakaMargaret C Bruce
Nov 13, 2001·Journal of the American College of Cardiology·S ZevinN L Benowitz
Jul 19, 2011·The Annals of Occupational Hygiene·Tracy L KirkhamPaul A Demers
Jan 30, 2014·International Journal of Environmental Research and Public Health·Yi SunMarkus Mattenklott
Feb 12, 2010·Archives of Environmental & Occupational Health·Dikmenoğlu Neslihan, Seringeç Nurten
Apr 17, 2007·The American Journal of the Medical Sciences·Tze-Ming ChenWare G Kuschner
Sep 16, 2004·QJM : Monthly Journal of the Association of Physicians·J E SharmanJ S Coombes
Feb 14, 1998·Scandinavian Journal of Social Medicine·D R RaglandJ M Fisher
Jan 1, 1986·American Journal of Industrial Medicine·E Feuer, K Rosenman
Jan 1, 1984·American Journal of Industrial Medicine·T L ThomasJ F Fraumeni
Jan 1, 1996·International Archives of Occupational and Environmental Health·W Stöber, U R Abel
Apr 17, 2003·Archives of Environmental Health·James E SharmanDavid I Fraser
Jan 1, 1992·International Archives of Occupational and Environmental Health·P T Scheepers, R P Bos
Mar 10, 1999·The American Journal of Physiology·S R ThomH Ischiropoulos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Frontiers in Bioscience : a Journal and Virtual Library
Hiroaki MinamiR John Solaro
American Journal of Industrial Medicine
F Stern, M Haring-Sweeney
Environmental Health Perspectives
Francine LadenEric Garshick
© 2021 Meta ULC. All rights reserved