Exposure to bisphenol A during pregnancy and child neuropsychological development in the INMA-Sabadell cohort

Environmental Research
Maribel CasasMartine Vrijheid

Abstract

Bisphenol A (BPA) may be a neurodevelopmental toxicant, but evidence is not consistent in terms of the sex-specific patterns of the associations and the specific behavioral or cognitive domains most affected. To examine the effects of prenatal BPA exposure on cognitive, psychomotor, and behavioral development in 438 children at 1, 4 and 7 years of age. BPA was measured in spot urine samples collected in trimester 1 and 3 of pregnancy from women participating in the INMA-Sabadell birth cohort study. Cognitive and psychomotor development was assessed at 1 and 4 years using psychologist-based scales. Attention deficit hyperactivity disorder (ADHD) symptoms and other behavioral problems were assessed at 4 years by teachers and at 7 years by parents using questionnaire-based rating scales. Geometric mean creatinine-adjusted BPA concentration of the averaged samples was 2.6 μg/g creatinine. BPA exposure was not associated with the cognitive scores or their subscales at 1 and 4 years of age. At 1 year of age, exposure in the highest tertile of BPA concentrations was associated with a reduction of psychomotor scores (T3 vs T1 β=-4.28 points, 95% CI: -8.15, -0.41), but there was no association with psychomotor outcomes at 4 years. At 4 ...Continue Reading

References

Jul 1, 1997·Journal of Child Psychology and Psychiatry, and Allied Disciplines·R Goodman
Oct 5, 2001·Clinical Psychology Review·W J GianarrisL Greene
Oct 22, 2002·Chemical Research in Toxicology·Wolfgang VölkelWolfgang Dekant
Jun 6, 2007·Prevention Science : the Official Journal of the Society for Prevention Research·John W GrahamTamika D Gilreath
Sep 11, 2007·Reproductive Toxicology·Laura N VandenbergWade V Welshons
Nov 1, 2008·BMC Medical Research Methodology·Ian Shrier, Robert W Platt
Jan 24, 2009·Environmental Health Perspectives·Olivier BoucherCélyne H Bastien
Jul 1, 2009·BMJ : British Medical Journal·Jonathan A C SterneJames R Carpenter
Jan 6, 2010·Environmental Health Perspectives·Joe M BraunBruce P Lanphear
Oct 30, 2010·Hormones and Behavior·Jennifer T WolstenholmeJessica J Connelly
Feb 22, 2011·Brain, Behavior, and Immunity·Marija Kundakovic, Frances A Champagne
Apr 8, 2011·International Journal of Epidemiology·Mònica GuxensUNKNOWN INMA Project
Aug 4, 2011·Epidemiology·Johannes TextorSven Knüppel
Aug 23, 2011·Neurotoxicology and Teratology·Kimberly YoltonJane Khoury
May 1, 2012·Environmental Health Perspectives·Frederica PereraShuang Wang
Jul 18, 2012·Pediatrics·Nancy N MaserejianDavid C Bellinger
Dec 12, 2012·American Journal of Epidemiology·A Z PollackE F Schisterman
Mar 1, 2013·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Soon-Beom HongSoo-Churl Cho
May 30, 2013·Proceedings of the National Academy of Sciences of the United States of America·Marija KundakovicFrances A Champagne
Jul 23, 2013·Environmental Research·Kim G HarleyBrenda Eskenazi
Sep 3, 2013·Reproductive Toxicology·Johanna R Rochester
Oct 9, 2013·Hormones and Behavior·Jennifer T WolstenholmeEmilie F Rissman
Dec 18, 2013·Journal of the American Academy of Child and Adolescent Psychiatry·Susanna N VisserStephen J Blumberg
Feb 22, 2014·Lancet Neurology·Philippe Grandjean, Philip J Landrigan
Oct 14, 2014·Neurotoxicology·Sarah F EvansShanna H Swan
Mar 1, 2015·Environmental Research·Emily L RoenFrederica P Perera
Jul 1, 2015·Neurotoxicology·Vicente MustielesMariana F Fernández

❮ Previous
Next ❯

Citations

Dec 15, 2015·Neurotoxicology·R Perez-LobatoM F Fernandez
May 25, 2016·International Journal of Hygiene and Environmental Health·Martine VrijheidMark Nieuwenhuijsen
Nov 20, 2016·Nature Reviews. Endocrinology·Joseph M Braun
Oct 30, 2016·The Journal of Pharmacology and Experimental Therapeutics·Amanda Crider, Anilkumar Pillai
Jun 29, 2017·Environmental Health Perspectives·Joseph M BraunBruce P Lanphear
Dec 13, 2017·Development and Psychopathology·Maria A Gartstein, Michael K Skinner
Sep 25, 2017·Environmental Health Perspectives·Claire PhilippatUNKNOWN EDEN Mother–Child Study Group
Feb 21, 2018·Environmental Health : a Global Access Science Source·Dorothy NakiwalaUNKNOWN EDEN mother-child study group
Mar 25, 2018·Endocrine Connections·Bilal B MughalBarbara A Demeneix
Mar 8, 2019·Reviews on Environmental Health·Alexandra N DavisJane A McElroy
Nov 19, 2019·Annual Review of Physiology·Dinushan Nesan, Deborah M Kurrasch
Apr 25, 2020·Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology·Seung-Jin YooKyoung Min Kim
Jun 3, 2020·Environmental Science and Pollution Research International·Yonghong LiRuifang Fan
Jul 28, 2020·Environmental Health Perspectives·Michiel A van den DriesAnjoeka Pronk
Oct 17, 2019·World Journal of Pediatrics : WJP·Joyce TienJianghong Liu
Aug 8, 2018·Medical Sciences : Open Access Journal·Andrea AvecillaVincent Avecilla
Jan 6, 2021·International Journal of Molecular Sciences·Wu Jeong HwangJun Soo Kwon
Mar 14, 2021·Environmental Health : a Global Access Science Source·Julie Bang HansenTina Kold Jensen
Apr 4, 2021·International Journal of Environmental Research and Public Health·Machiko Minatoya, Reiko Kishi
Apr 25, 2021·European Journal of Pediatrics·Sarah ZulkifliNoor Shafina Mohd Nor

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain developing: Influences & Outcomes

This feed focuses on influences that affect the developing brain including genetics, fetal development, prenatal care, and gene-environment interactions. Here is the latest research in this field.

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.