Abstract
Amongst medical exams requiring ionizing radiation, computed tomography (CT) scans are used more frequently, including in children. These CT examinations are associated with absorbed doses that are much higher than those associated with conventional radiology. In comparison to adults, children have a greater sensitivity to radiation and a longer life span with more years at cancer risks. Five epidemiological studies on cancer risks after CT scan exposure during childhood were published between 2012 and 2015. The results of these studies are consistent and show an increase of cancer risks in children who have been exposed to several CT scans. However, methodological limits due to indication bias, retrospective assessment of radiation exposure from CT scans and lack of statistical power are to be taken into consideration. International projects such as EPI-CT (Epidemiological study to quantify risks for pediatric computerized tomography and to optimize dose), with a focus on dosimetric reconstruction and minimization of bias will provide more precise results. In the meantime, available results reinforce the necessity of justification and optimization of doses.
References
Feb 13, 2001·AJR. American Journal of Roentgenology·D BrennerW Berdon
Aug 29, 2007·Radiation Research·D L PrestonK Kodama
Dec 17, 2008·Pediatric Radiology·Dorothy BulasBeverly Wood
Jan 14, 2009·Blood·Sébastien MalingeJohn D Crispino
Apr 29, 2009·Radiation Research·Gaël P HammerMaria Blettner
Aug 19, 2009·Heart·Lamia Ait-AliEugenio Picano
Dec 17, 2009·Archives of Internal Medicine·Amy Berrington de GonzálezCharles Land
Apr 2, 2011·The Lancet Oncology·Amy Berrington de GonzalezElaine Ron
Dec 23, 2011·The British Journal of Radiology·M-O BernierD Laurier
Jul 14, 2012·Radiology Research and Practice·Mark S PearceLouise Parker
Oct 3, 2012·The Lancet Oncology·Jean-François BrasmeMartin Chalumeau
Feb 23, 2013·International Journal of Environmental Research and Public Health·Isabelle Thierry-ChefAusrele Kesminiene
Mar 26, 2013·BMC Public Health·Helene BayssonMarie-Odile Bernier
May 23, 2013·BMJ : British Medical Journal·John D MathewsSarah C Darby
Jun 12, 2013·JAMA Pediatrics·Diana L MigliorettiRebecca Smith-Bindman
Oct 10, 2013·Radiation and Environmental Biophysics·Neige JournyMarie-Odile Bernier
Feb 27, 2014·British Journal of Cancer·W-Y HuangC-H Kao
Mar 7, 2014·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Linda WalshRichard Wakeford
Mar 22, 2014·Pediatric Cardiology·S BarnaouiB Aubert
May 27, 2015·British Journal of Cancer·C R Muirhead
May 27, 2015·British Journal of Cancer·E CardisM B de Basea
May 27, 2015·British Journal of Cancer·N JournyM-O Bernier
Citations
Jan 10, 2017·Clinical Radiology·J DaviesJ Evanson
Dec 29, 2016·European Journal of Radiology·Lorenzo FaggioniDavide Caramella
Nov 27, 2016·La Radiologia medica·Paolo TomàClaudio Granata
Oct 28, 2018·Current Medical Research and Opinion·Li ZhangShu-Jing Yu
Sep 11, 2020·Pediatric Radiology·Kossi D AbaloMarie-Odile Bernier
Mar 17, 2020·Journal of Pediatric Surgery·Mark KashtanShawn Rangel
Aug 5, 2017·Pediatrics·Jay PershadPaul Klimo