PMID: 15232409Jul 3, 2004Paper

Exposure to NO2 and nitrous acid and respiratory symptoms in the first year of life

Epidemiology
Robert T van StrienBrian P Leaderer

Abstract

Effects of nitrogen dioxide (NO2) on respiratory health have been the subject of extensive research. The outcomes of these studies were not consistent. Exposure to nitrous acid, which is a primary product of combustion, and is also formed when NO2 reacts with water, may play an important role in respiratory health. We estimate the independent effects of exposure to nitrogen dioxide and nitrous acid on respiratory symptoms during the first year of life. Nitrogen dioxide and nitrous acid concentrations were measured once (1996-1998) in the homes of 768 infants who were at risk for developing asthma. Infants were living in southern New England. The frequency of respiratory symptoms in these children was recorded during the first year of life. Infants living in homes with an NO2 concentration exceeding 17.4 ppb (highest quartile) had a higher frequency of days with wheeze (rate ratio = 2.2; 95% confidence interval = 1.4-3.4), persistent cough (1.8; 1.2-2.7), and shortness of breath (3.1; 1.8-5.6) when compared with infants in homes that had NO2 concentrations lower than 5.1 ppb (lowest quartile), controlling for nitrous acid concentration. Nitrous acid exposure was not independently associated with respiratory symptoms. Among infan...Continue Reading

References

Jul 16, 1977·British Medical Journal·R J MeliaA V Swan
Oct 1, 1976·American Industrial Hygiene Association Journal·E D PalmesC Tomczyk
May 1, 1992·Journal of the Air & Waste Management Association·V HasselbladD J Kotchmar
Jul 25, 1991·American Journal of Epidemiology·L M NeasB G Ferris
Nov 1, 1990·The American Review of Respiratory Disease·L DijkstraJ S Boleij
Aug 1, 1986·American Journal of Epidemiology·B P LeadererJ A Stolwijk
May 1, 1987·American Journal of Epidemiology·B BrunekreefP Clausing
Apr 1, 1995·Environmental Health Perspectives·W S BeckettB P Leaderer
May 1, 1995·American Journal of Respiratory and Critical Care Medicine·T R RasmussenS Kjaergaard
Jan 19, 1995·The New England Journal of Medicine·F D MartinezW J Morgan
Nov 1, 1993·The American Review of Respiratory Disease·J M SametJ D Spengler
Aug 1, 1993·The American Review of Respiratory Disease·J M SametB J Skipper
Mar 1, 1997·American Journal of Respiratory and Critical Care Medicine·V StrandG Bylin
May 26, 1998·The Journal of Allergy and Clinical Immunology·S M TariqD W Hide
Mar 3, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M T Krishna, S T Holgate
Sep 1, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B Brunekreef
Feb 12, 2002·Environmental Health Perspectives·Kiyoung LeeJohn D Spengler
Oct 16, 2002·American Journal of Respiratory and Critical Care Medicine·Elizabeth W TricheBrian P Leaderer

❮ Previous
Next ❯

Citations

Jun 16, 2012·Journal of the Air & Waste Management Association·TaeSeok OhJeong Tai Kim
Dec 17, 2005·Current Opinion in Pulmonary Medicine·Robert S Byrd, Jesse P Joad
Oct 29, 2005·American Journal of Respiratory and Critical Care Medicine·Kathleen BelangerBrian P Leaderer
Apr 5, 2007·BMC Medical Genetics·Melinda M PettigrewBrian P Leaderer
May 12, 2006·Journal of Occupational and Environmental Medicine·Monika NitschkeJanet E Hiller
Aug 7, 2010·Inhalation Toxicology·Masayuki OhyamaNorimichi Takenaka
Apr 17, 2007·The American Journal of the Medical Sciences·Tze-Ming ChenWare G Kuschner
Sep 6, 2011·The Science of the Total Environment·Ana EspluguesCarmen Iñiguez
Sep 21, 2010·International Journal of Hygiene and Environmental Health·Joachim Heinrich
Mar 5, 2010·The Journal of Allergy and Clinical Immunology·David Peden, Charles E Reed
Dec 25, 2007·The Journal of Allergy and Clinical Immunology·Jonathan A BernsteinSusan M Tarlo
Dec 19, 2006·Pulmonary Pharmacology & Therapeutics·Jesse P JoadAnn C Bonham
Feb 12, 2009·Pediatric Pulmonology·Virginia Fuentes-LeonarteFerran Ballester
Dec 24, 2009·Indoor Air·O Raaschou-NielsenH Bisgaard
Oct 14, 2009·Statistics in Medicine·Theodore R HolfordBrian P Leaderer
Feb 8, 2005·The Journal of Allergy and Clinical Immunology·David B Peden
Sep 21, 2006·The American Journal of Emergency Medicine·Hai-Lun SunKo-Huang Lue
Oct 13, 2005·International Journal of Hygiene and Environmental Health·M MommersM Weishoff-Houben
Apr 15, 2015·International Journal of Environmental Research and Public Health·Evridiki PatelarouFrank J Kelly
Feb 16, 2015·Environmental Research·Fabio CibellaGiovanni Viegi
Aug 27, 2014·Paediatric Respiratory Reviews·Guodong DingYixiao Bao
Aug 5, 2016·Environmental Science and Pollution Research International·Reza Fouladi FardMohammad Sadegh Hassanvand
Sep 28, 2020·Environmental Health and Preventive Medicine·Masayuki OhyamaShuichi Adachi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.