Exposure to organophosphate flame retardant chemicals in the U.S. general population: Data from the 2013-2014 National Health and Nutrition Examination Survey

Environment International
Maria OspinaAntonia M Calafat

Abstract

Use of organophosphate flame retardants (OPFRs) including tris(1,3-dichloro-2-propyl) phosphate, triphenyl phosphate, tris(1-chloro-2-propyl) phosphate, and tris-2-chloroethyl phosphate, in consumer products is on the rise because of the recent phase out of polybrominated diphenyl ether (PBDE) flame retardants. Some of these chemicals are also used as plasticizers or lubricants in many consumer products. To assess human exposure to these chlorinated and non-chlorinated organophosphates, and non-PBDE brominated chemicals in a representative sample of the U.S. general population 6years and older from the 2013-2014 National Health and Nutrition Examination Survey (NHANES). We used solid-phase extraction coupled to isotope dilution high-performance liquid chromatography-tandem mass spectrometry after enzymatic hydrolysis of conjugates to analyze 2666 NHANES urine samples for nine biomarkers: diphenyl phosphate (DPHP), bis(1,3-dichloro-2-propyl) phosphate (BDCIPP), bis-(1-chloro-2-propyl) phosphate (BCIPP), bis-2-chloroethyl phosphate (BCEP), di-n-butyl phosphate (DNBP), di-p-cresylphosphate (DpCP), di-o-cresylphosphate (DoCP), dibenzyl phosphate (DBzP), and 2,3,4,5-tetrabromobenzoic acid (TBBA). We calculated the geometric mean (GM...Continue Reading

Citations

Mar 13, 2018·Toxicological Sciences : an Official Journal of the Society of Toxicology·Constance A MitchellDavid C Volz
Jan 26, 2018·International Journal of Environmental Research and Public Health·Binnian WeiAndrew J Hyland
May 22, 2019·Journal of Occupational and Environmental Hygiene·Cheryl Fairfield EstillAntonia M Calafat
Jul 19, 2019·American Journal of Public Health·Kathryn M RodgersRuthann A Rudel
Aug 2, 2019·Toxicological Sciences : an Official Journal of the Society of Toxicology·Aalekhya ReddamDavid C Volz
Aug 12, 2018·Archives of Toxicology·Anne-Marie SaillenfaitJean-Philippe Sabaté
Nov 23, 2019·Current Environmental Health Reports·Brett T DohertyKate Hoffman
Aug 8, 2020·Environmental Science. Processes & Impacts·Naga Raju MaddelaMallavarapu Megharaj
Nov 3, 2020·Environment International·Michiel BastiaensenAdrian Covaci
Jul 18, 2020·Environment International·Kai LuoJun Zhang
Aug 11, 2020·Environment International·Stephanie C HammelKate Hoffman
Apr 12, 2021·The Science of the Total Environment·Giehae ChoiStephanie M Engel
Jun 14, 2021·International Journal of Hygiene and Environmental Health·Alexander C MayerAndreas Sjodin
Jul 28, 2021·Environment International·Barrett M WelchKelly K Ferguson
Jun 5, 2020·Environmental Science & Technology Letters·Arlene BlumMarta Venier
Jul 11, 2019·Environmental Science & Technology·Carolyn M PoutasseKim A Anderson
Sep 4, 2020·Chemical Research in Toxicology·Binnian WeiAndrew Hyland
Aug 27, 2021·Archives of Toxicology·Enzo Zini Moreira SilvaDaniela Morais Leme
Oct 7, 2021·Environmental Health Perspectives·Heather B PatisaulHeather M Stapleton

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.