Exposures of 129 preschool children to organochlorines, organophosphates, pyrethroids, and acid herbicides at their homes and daycares in North Carolina

International Journal of Environmental Research and Public Health
Marsha K MorganJane C Chuang

Abstract

Few data exist on the concurrent exposures of young children to past-use and current-use pesticides in their everyday environments. In this further analysis of study data, we quantified the potential exposures and intake doses of 129 preschool children, ages 20 to 66 months, to 16 pesticides (eight organochlorines, two organophosphates, three pyrethroids, and three acid herbicides). Environmental samples (soil, dust, outdoor air, and indoor air) and personal samples (hand wipes, solid food, and liquid food) were collected at 129 homes and 13 daycare centers in six counties in North Carolina between 2000 and 2001. α-Chlordane, γ-chlordane, heptachlor, chlorpyrifos, diazinon, cis-permethrin, trans-permethrin, and 2,4-dichlorophenoxyacetic acid (2,4-D) were detected ≥50% in two or more media in both settings. Of these pesticides, the children's estimated median potential intake doses through dietary ingestion, nondietary ingestion, and inhalation routes were the highest for 2,4-D and cis/trans-permethrin (both 4.84 ng/kg/day), cis/trans-permethrin (2.39 ng/kg/day), and heptachlor (1.71 ng/kg/day), respectively. The children's estimated median potential aggregate intake doses by all three routes were quantifiable for chlorpyrifos (...Continue Reading

References

Mar 16, 1979·Science·J Smith
Aug 1, 1992·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·B H WoollenJ E Lesser
Mar 30, 1984·Toxicology and Applied Pharmacology·R J NolanJ H Saunders
Feb 1, 1983·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·C V Eadsforth, M K Baldwin
Apr 6, 2001·The Annals of Occupational Hygiene·J H RossR I Krieger
Jan 16, 2002·Journal of Exposure Analysis and Environmental Epidemiology·N K WilsonC Lyu
Apr 18, 2003·Nature·Jeanne Mager StellmanCarrie Tomasallo
May 14, 2003·Journal of Exposure Analysis and Environmental Epidemiology·Nancy K WilsonMarsha K Morgan
Sep 16, 2004·Journal of Exposure Analysis and Environmental Epidemiology·Marsha K MorganChristopher W Lyu
Sep 14, 2007·Journal of Exposure Science & Environmental Epidemiology·Nicolle S TulveAaron Hilliard
Jan 3, 2008·Journal of Exposure Science & Environmental Epidemiology·Marsha K MorganNancy K Wilson
Apr 22, 2010·Journal of Exposure Science & Environmental Epidemiology·Nicolle S TulveCarry W Croghan
May 27, 2010·Journal of Exposure Science & Environmental Epidemiology·Marsha K MorganNancy K Wilson
Jan 19, 2012·Environmental Health Perspectives·Alison L CluneDana Boyd Barr
Aug 27, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Marsha K Morgan, Paul A Jones

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Citations

Oct 13, 2014·Current Opinion in Pharmacology·Naila KhalilMiryoung Lee
Jun 25, 2016·Environmental Science & Technology·Robert B GunierMary H Ward
Apr 19, 2015·Environmental Health : a Global Access Science Source·Nicole C DezielMary H Ward
Jul 6, 2017·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Severyn SalisGianfranco Brambilla
Oct 23, 2019·Journal of Exposure Science & Environmental Epidemiology·Ellen M CooperHeather M Stapleton
Jun 7, 2018·Environmental Science and Pollution Research International·Chien-Che HungLih-Ming Yiin
Nov 22, 2017·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Judy S LaKindJoshua S Naiman
Aug 12, 2017·Risk Analysis : an Official Publication of the Society for Risk Analysis·Marie HermantVirginie Desvignes
May 13, 2019·Environmental Science and Pollution Research International·Rémi BérangerBeatrice Fervers

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