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Expression noise facilitates the evolution of gene regulation

bioRxiv

Jul 18, 2014

Luise WolfErik J van Nimwegen

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Abstract

In studies of gene regulation, it is often tacitly assumed that the interactions between transcriptional regulators and their target promoters are finely tuned to ensure condition-appropriate gene expression of the targets. However, how natural selection might evolve such precise regula...read more

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Gene Expression
Promoter
Theoretical Model
Escherichia coli
Entamoeba coli
Transcription, Genetic
20
14
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  • Expression noise facilitates the evolution of gene regulation

    bioRxiv

    Jul 18, 2014

    Luise WolfErik J van Nimwegen

    PMID: 990007237

    DOI: 10.1101/007237

    Abstract

    In studies of gene regulation, it is often tacitly assumed that the interactions between transcriptional regulators and their target promoters are finely tuned to ensure condition-appropriate gene expression of the targets. However, how natural selection might evolve such precise regula...read more

    Mentioned in this Paper

    Gene Expression
    Promoter
    Theoretical Model
    Escherichia coli
    Entamoeba coli
    20
    14
    Paper Details
    References
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