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Expression noise facilitates the evolution of gene regulation

bioRxiv

Jul 18, 2014

Luise WolfErik van Nimwegen

Abstract

In studies of gene regulation, it is often tacitly assumed that the interactions between transcriptional regulators and their target promoters are finely tuned to ensure condition-appropriate gene expression of the targets. However, how natural selection might evolve such precise regula...read more

Mentioned in this Paper

Study
Transcriptional Regulation
Theoretical Model
Genes
Regulation of Biological Process
Transcription, Genetic
Promoter
Theoretical Study
Adverse Effects
Gene Expression
20
50
Paper Details
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Expression noise facilitates the evolution of gene regulation

bioRxiv

Jul 18, 2014

Luise WolfErik van Nimwegen

PMID: 990007237

DOI: 10.1101/007237

Abstract

In studies of gene regulation, it is often tacitly assumed that the interactions between transcriptional regulators and their target promoters are finely tuned to ensure condition-appropriate gene expression of the targets. However, how natural selection might evolve such precise regula...read more

Mentioned in this Paper

Study
Transcriptional Regulation
Theoretical Model
Genes
Regulation of Biological Process
Transcription, Genetic
Promoter
Theoretical Study
Adverse Effects
Gene Expression
20
50
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
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