Expression of AMPA-type glutamate receptors in pretectal nuclei of the chick brain

Brain Research Bulletin
Cláudio A B ToledoLuiz R G Britto

Abstract

The pretectum is involved in the neural integration of visually dependent responses. We studied the occurrence of immunoreactivity for subunits that constitute the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-type glutamate receptors in the chick pretectum. Four pretectal nuclei of the chick brain, namely, the nucleus pretectalis, the nucleus spiriformis lateralis, the nucleus spiriformis medialis, and the nucleus lentiformis mesencephali, were included in the study, and they all showed AMPA-positive neurons. GluR1- and GluR2/3-positive neurons and fibers were detected in the pretectal nucleus, with GluR4-positive neurons forming a cap surrounding the main core of that nucleus. The lateral spiriform nucleus showed immunoreactivity only for GluR2/3 and GluR4, and the medial spiriform nucleus showed immunoreactivity only for GluR1 and GluR2/3. GluR1-positive neurons and fibers were found in the nucleus lentiformis mesencephali, but only GluR2/3-positive neurons and GluR4-positive fibers were detected into that nucleus. The different patterns of distribution of GluR subunits within the pretectal nuclei suggest different AMPA-triggered properties among their neurons. This suggests that the four pretectal nuclei ...Continue Reading

References

Oct 1, 1989·Trends in Neurosciences·R L AlbinJ B Penney
Mar 1, 1988·The Journal of Comparative Neurology·P D Gamlin, D H Cohen
Jul 10, 1984·The Journal of Comparative Neurology·P D GamlinD H Cohen
Jan 1, 1997·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·R S Pires, L R Britto
Dec 22, 1998·Brain Research. Brain Research Reviews·A ReinerC L Veenman

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Citations

Nov 15, 2003·Journal of Chemical Neuroanatomy·Renato F SantanaCláudio A B Toledo
Jun 2, 2009·Journal of Chemical Neuroanatomy·Yasuro Atoji, Mohammad Rafiqul Islam
Oct 13, 2005·Brain, Behavior and Evolution·Antonio V LaverghettaAnton Reiner

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