Expression of antimicrobial peptide genes after infection by parasitoid wasps in Drosophila

Developmental and Comparative Immunology
E NicolasBruno Lemaitre

Abstract

We report here the use of a specific beta-galactosidase staining assay and Northern blotting technique to examine the expression of three genes encoding either antibacterial peptides (diptericin, cecropin A) or an antifungal peptide (drosomycin) in Drosophila following infection by larval and pupal parasitoids. The results show that the genes encoding these peptides are either not induced or minimally induced in wasp-infected hosts, but remain responsive and are induced upon microbial challenge. As the parasitoids elicit a cellular response, our data suggest that the antimicrobial responses are activated and/or regulated by mechanisms that are independent of those mediating cellular encapsulation.

References

Mar 1, 1992·Developmental and Comparative Immunology·T M Rizki, R M Rizki
Feb 15, 1992·European Journal of Biochemistry·Y TryseliusD Hultmark
May 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·B Lemaitre, D Coen
Jul 11, 1984·Nucleic Acids Research·P O O'Connell, M Rosbash
Oct 22, 1982·Science·G M Rubin, A C Spradling
Oct 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·R M Rizki, T M Rizki
Oct 10, 1995·Proceedings of the National Academy of Sciences of the United States of America·B LemaitreJ A Hoffmann
Feb 1, 1995·Current Opinion in Immunology·J A Hoffmann
Apr 15, 1994·Annals of the New York Academy of Sciences·T M Rizki, R M Rizki
Feb 1, 1996·Biochemical Society Transactions·S Govind

❮ Previous
Next ❯

Citations

Oct 26, 2000·Trends in Genetics : TIG·R S Khush, B Lemaitre
Feb 26, 2000·Heredity·M D Fellowes, H C Godfray
Aug 30, 2011·Molecular Biology and Evolution·Erin S Keebaugh, Todd A Schlenke
Oct 18, 2012·Journal of Insect Physiology·Sébastien J M Moreau
Aug 17, 2000·Nitric Oxide : Biology and Chemistry·A J NappiY Carton
Feb 24, 2001·The Journal of Parasitology·E Vass, A J Nappi
Feb 22, 2021·Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics·Sheng ShengFu-An Wu
Aug 25, 2004·Developmental and Comparative Immunology·Y CartonM Poirie

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.