PMID: 16507411Mar 2, 2006Paper

Expression of c-erbB receptors, MMPs and VEGF in head and neck squamous cell carcinoma

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
S C Lim

Abstract

Head and neck squamous cell carcinomas (HNSCC) are characterized by a marked propensity for local invasion and cervical lymph node metastasis. The aim of this article was to review the expression of epidermal growth factor receptor (EGFR), c-erbB-2, vascular endothelial growth factor (VEGF) and matrix metal loproteinases (MMPs) in HNSCC patients and to study their possible correlation to various clinicopathologic parameters. Based on this review, the expression of EGFR, c-erbB-2, VEGF, or MMPs play important roles for tumor growth, invasion and metastasis in HNSCC. c-erbB receptors, MMPs and VEGF might aid the clinician in the selection of an appropriate therapy for individual patients and help to predict the prognosis of patients.

References

Jan 1, 1990·Cancer·A McCannD N Carney
Jun 17, 2000·Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrès Dans Les Recherches Sur Le Cancer·S A Eccles
Jul 19, 2002·International Journal of Cancer. Journal International Du Cancer·Pornchai O-CharoenratSuzanne Eccles

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Citations

Jun 6, 2015·Archives of Pathology & Laboratory Medicine·Lizandra JimenezJeffrey E Segall
Apr 14, 2012·Acta Oto-laryngologica·Marco LionelloGino Marioni
Jan 26, 2010·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·M T RuizE M Goloni-Bertollo
Jan 18, 2008·Technology in Cancer Research & Treatment·K P WithrowE L Rosenthal

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