Expression of cell adhesion molecules in lung cancer cell lines

Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie
S HornJ Lorenz

Abstract

Cell adhesion mechanisms are among the basic aspects in organism development. Adhesion molecules are involved in the building of complex structures and of association of the tissue. They also mediate as substratum adhesion molecules and are involved in the building of the scaffold. The process of tumor growth and metastasis is a complex cascade of events (FIDLER 1989). For many of these steps the tumor cells must be able to change their degree of adherence. Tumor progression and metastatic dissemination are tightly linked with the ability of the tumor cells to interact with other cells and with the extracellular matrix. The first step of metastasis is the active migration of tumor cells into the surrounding tissue.

References

Mar 1, 1991·American Journal of Respiratory Cell and Molecular Biology·S M Albelda
Nov 1, 1989·Cytometry·I J Fidler

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Citations

Jun 15, 2013·Histochemistry and Cell Biology·Hayan Yi, Nam-On Ku
Aug 4, 2021·Journal of Cell Science·Sujin KimNam-On Ku

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Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

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