Expression of creatine kinase isoenzyme during oogenesis and embryogenesis in the mouse

Developmental Biology
M R IyengarRichard M Schultz

Abstract

Creatine kinase activity was discovered in the growing mouse oocyte and in the preimplantation embryo. Changes in the enzyme activity during the growth and maturation of the egg and during the development of the embryo up to the blastocyst stage were determined. Close similarity of the protein to the brain-type isoenzyme of creatine kinase was established immunochemically. The kinetic parameters of the brain-type isoenzyme (M. R. Iyengar, C. E. Fluellen, and C. W. L. Iyengar, 1982, J. Muscle Cell Motil. 3, 231-246) and the pattern of development-associated changes in activity suggest a possible role for creatine kinase in maintaining the reported high ATP/ADP ratio (L. Ginsberg and N. Hillman, 1975, J. Reprod. Fertil. 43, 83-90), which is essential for the biosynthetic activities of the embryo.

References

May 1, 1978·Journal of Reproduction and Fertility·A MukherjeeZ Dickmann
Apr 1, 1975·Journal of Reproduction and Fertility·L Ginsberg, N Hillman
Sep 1, 1974·Developmental Biology·R Bachvarova
Oct 1, 1974·Developmental Biology·C J Epstein, S A Smith
Sep 1, 1973·Biulleten' eksperimental'noĭ biologii i meditsiny·I P AshmarinI S Freĭdlin
Apr 1, 1971·Journal of Reproduction and Fertility·P Quinn, R G Wales
Jan 1, 1966·The Proceedings of the Nutrition Society·C E Lucas
Jun 1, 1967·Journal of Reproduction and Fertility·R L Brinster
Apr 29, 1967·Nature·B MorelandR Virden
Jul 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·R NuccitelliG B Matson
Jun 1, 1982·Journal of Muscle Research and Cell Motility·M R IyengarC Iyengar
Jun 16, 1980·Biochemical and Biophysical Research Communications·M R IyengarC W Iyengar
May 25, 1957·Nature·W K WHITTEN
Aug 1, 1964·Developmental Biology·H M EPPENBERGERH AEBI
Mar 1, 2001·Journal of Clinical Neuromuscular Disease·B Katiriji, M M Al Jaberi

❮ Previous
Next ❯

Citations

Aug 20, 2010·Journal of Assisted Reproduction and Genetics·Maw-Sheng LeeEn-Hui Cheng
Dec 1, 1992·Mutation Research·P M Wassarman, R A Kinloch
Oct 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·H J LeeM R Iyengar
Feb 3, 2016·Proceedings of the National Academy of Sciences of the United States of America·Rossana SussarelluArnaud Huvet
Jan 3, 2013·Molecular Reproduction and Development·Katherine E ForseyHenry J Leese
Sep 22, 2001·Biology of Reproduction·J YuR M Schultz
Jun 13, 2003·Biology of Reproduction·Patrick M MartinLon J Van Winkle
Oct 1, 1984·Journal of Muscle Research and Cell Motility·M R Iyengar
Feb 6, 2021·Nutrients·Anna Maria MucciniStacey J Ellery
Oct 1, 1987·The American Journal of Physiology·J C CrossH R Behrman
Jun 30, 1995·Biochimica Et Biophysica Acta·K SteeghsB Wieringa
Nov 26, 2018·Theriogenology·H B A BastosR C Mattos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.