PMID: 11335117May 4, 2001Paper

Expression of DWnt6, DWnt10, and DFz4 during Drosophila development

Mechanisms of Development
K JansonElizabeth L Wilder

Abstract

Members of the Wnt gene family encode secreted proteins that signal through the Frizzled family of receptors to function in many aspects of development. In this study, we have analyzed the expression of two Wnt genes and one Frizzled family member that were recently identified through the Drosophila genome sequencing project. We show that DWnt6 is only weakly expressed in developing embryos, with transcripts faintly detected in the gut. By late third instar however, this gene is expressed in a pattern that is identical to that of wingless (wg) in the imaginal discs. DWnt10 is expressed in the embryonic mesoderm, central nervous system and gut, whereas its expression is below the levels of our detection in third instar imaginal discs. We find that DFz4 is also expressed in a dynamic pattern in the mesoderm, gut, and central nervous system.

Citations

Nov 22, 2001·Proceedings of the National Academy of Sciences of the United States of America·M Llimargas, P A Lawrence
Oct 5, 2013·BMC Biology·Nikolaos DoumpasAurelio A Teleman
Apr 19, 2005·Genetics·Matthew J LavioletteBryan A Stewart
Jun 3, 2015·Proceedings of the National Academy of Sciences of the United States of America·Shigeyuki KoshikawaSean B Carroll
Sep 10, 2014·Developmental Biology·Arnaud Martin, Robert D Reed
Jan 29, 2008·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Danielle L LaveryStefan Hoppler
Nov 8, 2005·Developmental Biology·Poongodi Geetha-LoganathanBodo Christ
Aug 6, 2010·Arthropod Structure & Development·Sophie MuratAlistair P McGregor
Oct 4, 2016·Evolution & Development·Savvas J ConstantinouTerri A Williams
Apr 16, 2003·Anatomy and Embryology·Marc Rodríguez-NiedenführBodo Christ
Nov 2, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·P S PereiraF Casares
Sep 3, 2002·The Journal of Biological Chemistry·Chi-hwa Wu, Roel Nusse
Dec 4, 2019·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Francisco HuizarJeremiah Zartman
Feb 23, 2020·Developmental Cell·Lara Barrio, Marco Milán
Apr 2, 2020·Developmental Biology·Michaela HolzemAlistair P McGregor

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