Expression of engrailed in an array of identified sensory neurons: comparison with position, axonal arborization, and synaptic connectivity

Journal of Neurobiology
J M BlagburnJ P Bacon

Abstract

engrailed (en) is expressed in the posterior region of embryonic segments and appendages of the cockroach, Periplaneta americana. By 23% of embryogenesis En immunoreactivity is apparent in the dorsal half of the cercus, appendages of segment A11. By 40% of development, En staining is present in the dorsomedial half of the cercus. The nucleus of the medial filiform hair sensory neuron (M), born in this region, expresses en strongly. Staining is never seen in the lateral neuron (L). En is expressed in M as the sensory axons enter the terminal ganglion and begin to form their different arborizations and synaptic connections. This pattern of expression persists through development to the second instar. In mutant animals with supernumerary filiform hair sensilla, En immunoreactivity is only seen in the medial neurons. In second-instar and adult cerci en expression is also seen in medially located neurons. We compared the levels of En staining in the array of 25 second instar neurons with their position, axonal arbor type, and synaptic connections. Staining intensity correlates with distance from the cercal midline, suggesting that en is regulated by other circumferential positional determinants. The expression of en does not correla...Continue Reading

References

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Nov 1, 1991·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·J M BlagburnJ P Bacon
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Citations

Nov 5, 1997·Developmental Biology·I Rajan, J L Denburg
Jul 4, 2008·Invertebrate Neuroscience : in·Jonathan M Blagburn
Jun 26, 2004·Annual Review of Neuroscience·Jonathan M Blagburn, Jonathan P Bacon
Jun 6, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·David BoothJonathan P Bacon
Dec 5, 2013·Journal of Visualized Experiments : JoVE·Josh S TitlowRobin L Cooper
Jul 30, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Shao-Pii OnnAnthony A Grace

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