Expression of galanin receptor-1 (GALR1) in the rat trigeminal ganglia and molar teeth

Neuroscience Research
Hironobu SuzukiTakeyasu Maeda

Abstract

The expression of galanin receptor-1 (GALR1) was investigated in the rat trigeminal ganglion by using immunocytochemistry and in situ hybridization. In addition, the regional distribution of GALR1-immunoreactive pulpal nerves and their ultrastructure were examined in the molar teeth. In the trigeminal ganglion, the immunoreactivity for GALR1 was recognizable in about 30% of the total number of neurons. Most of the cell bodies were small to medium in size. Analysis of serially cut sections alternately stained with GALR1 and galanin antisera demonstrated that some GALR1-positive cells displayed immunoreactivity for galanin. In situ hybridization analysis, expression of GALR1 mRNA was detected in trigeminal ganglion cells. The cell size distribution was similar to that of GALR1-immunoreactive cells. In the dental pulp, a small number of nerve fibers displayed immunoreactivity for GALR1. The labeled fibers formed terminal arbors in the coronal pulp around and within the odontoblast cell layer, but never penetrated into the predentin and dentin. Ultrastructurally, GALR1 immunoreactivity in the dental pulp was confined to the axoplasm of unmyelinated nerve fibers. The present study provided new evidence that unmyelinated primary affe...Continue Reading

References

Apr 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·Z Wiesenfeld-HallinT Bartfai
Jan 1, 1990·Histochemistry·A CasascoC Marchetti
Aug 1, 1985·Brain Research Bulletin·G Skofitsch, D M Jacobowitz
Jun 22, 1986·The Journal of Comparative Neurology·T MelanderA Rökaeus
Nov 1, 1987·Cell and Tissue Research·I StrömbergL Olson
Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M HsuH Fanger
Jun 15, 1984·Neuroscience Letters·A RökaeusV Mutt
Aug 1, 1984·Scandinavian Journal of Dental Research·M GrönbladA M Munck
Feb 1, 1982·Archivum Histologicum Japonicum = Nihon Soshikigaku Kiroku·T Gunji
Dec 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·T BartfaiR Corwin
Oct 11, 1994·Proceedings of the National Academy of Sciences of the United States of America·E Habert-OrtoliJ F Mayaux
Oct 1, 1994·Naunyn-Schmiedeberg's Archives of Pharmacology·W ReimannB Wilffert
Apr 1, 1995·The International Journal of Biochemistry & Cell Biology·K BedecsT Bartfai
Jun 1, 1993·Progress in Neurobiology·I MerchenthalerA Negro-Vilar
Jan 1, 1995·Journal of Molecular Neuroscience : MN·M C BurgevinE Habert-Ortoli
Dec 28, 1995·Brain Research. Molecular Brain Research·E M ParkerM E Goldstein
Dec 16, 1997·Proceedings of the National Academy of Sciences of the United States of America·Z Q XuT Hökfelt
Feb 3, 1999·Annals of the New York Academy of Sciences·D WynickV Pachnis
Dec 29, 1999·Brain Research·S O OgrenH Razani
Oct 4, 2000·Proceedings of the National Academy of Sciences of the United States of America·F E HolmesD Wynick
Sep 22, 1995·Regulatory Peptides·J N Crawley

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Citations

Dec 24, 2013·Experimental Cell Research·Françoise Bleicher
Jul 11, 2018·Cephalalgia : an International Journal of Headache·Karl Messlinger, Andrew F Russo
Mar 6, 2003·Microscopy Research and Technique·Margaret R ByersTakeyasu Maeda
Feb 24, 2020·Journal of Neural Transmission·Karl MesslingerAndrew F Russo

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