PMID: 7544758Sep 1, 1995Paper

Expression of glycoconjugates during intrahepatic bile duct development in the rat: an immunohistochemical and lectin-histochemical study

Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Takahiro SanzenYasuni Nakanuma

Abstract

We investigated the expression of carbohydrate residues on the developing intrahepatic bile ducts of rats. At 17 days of gestation, immature biliary cells around the portal vein close to the hepatic hilum assumed one of the following forms: slitlike lumen, incomplete, or complete bile ductule-like structures. These immature biliary elements then rapidly spread throughout the liver along with development. At birth, a few mature interlobular bile ducts became visible in the portal tracts. The cytoplasm of immature biliary cells stained weakly for concanavalin A, Erythrina crista galli agglutinin, and Limax flavus agglutinin, whereas the luminal surface of immature biliary cells at 17 days of gestation was positive for lectins, similar to those that are expressed on the luminal surface of the mature bile ducts, including concanavalin A, succinyl wheat germ agglutinin, Vicia villosa agglutinin, soybean agglutinin, peanut agglutinin, Erythrina crista galli agglutinin, and Limax flavus agglutinin. As development progressed, the number of lectins binding to the cytoplasm of biliary cells gradually increased, and lectin bindings to the luminal surface of biliary cells gradually became intense. Immature biliary epithelial cells of three...Continue Reading

References

Jan 1, 1992·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S S Spicer, B A Schulte
Jan 1, 1990·Pediatric Pathology·D S Heller, S N Thung
Nov 1, 1988·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·P Van EykenV J Desmet
Aug 1, 1989·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Y Nakanuma, M Sasaki
May 1, 1987·Kidney International·J F CrockerS C McCarthy
Jan 1, 1987·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·H Holthöfer, I Virtanen
Jan 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M SasakiY Nakanuma
Aug 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T Terada, Y Nakanuma

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Citations

Feb 14, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S Sell
Dec 1, 2000·Biochemical and Biophysical Research Communications·H Ouadid-AhidouchN Prevarskaya
Feb 6, 2010·World Journal of Gastroenterology : WJG·Ali Shorbagi, Yusuf Bayraktar
Mar 15, 2015·Stem Cell Research·Rohan ManoharEric Lagasse

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