Expression of growth differentiation factor-5 in the developing and adult rat brain

Brain Research. Developmental Brain Research
Gerard W O'KeeffeAideen M Sullivan

Abstract

Expression of the dopaminergic neurotrophin GDF-5 in developing rat ventral mesencephalon (VM) was found to begin at embryonic day (E) 12 and peak on E14, when dopaminergic neurones undergo terminal differentiation. In the adult rat, GDF-5 was found to be restricted to heart and brain, being expressed in many areas of the brain, including striatum and midbrain. This indicates a role for GDF-5 in the development and maintenance of dopaminergic neurones.

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Citations

Mar 30, 2010·Journal of Neural Transmission·David B O'SullivanAideen M Sullivan
Oct 5, 2007·Neuromolecular Medicine·Rakel López de MaturanaStuart Maudsley
Aug 23, 2011·Neurotoxicity Research·André ToulouseAideen M Sullivan
Apr 1, 2014·Neuromolecular Medicine·Shane V HegartyGerard W O'Keeffe
Feb 8, 2014·Molecular Neurobiology·Shane V HegartyGerard W O'Keeffe
Jun 22, 2011·Cytokine & Growth Factor Reviews·Aideen M Sullivan, André Toulouse
Oct 25, 2008·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Laurent DupoirieuxDidier Pourquier
Oct 16, 2007·Neuroscience Letters·Kevin B Clayton, Aideen M Sullivan
Mar 23, 2012·Journal of Cellular and Molecular Medicine·Daniel J CostelloAideen M Sullivan
Apr 11, 2012·Developmental Neurobiology·Allison M BondJohn A Kessler
Jan 27, 2005·Neuroscience Letters·Gerard W O' Keeffe, Aideen M Sullivan
Jan 22, 2008·Human Molecular Genetics·Frank PlögerStefan Mundlos
Jun 12, 2014·Journal of Neuroscience Research·Juliann D Jaumotte, Michael J Zigmond
Jun 9, 2021·Neural Regeneration Research·Susan R GouldingGerard W O'Keeffe

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