Expression of heat shock protein and hemoglobin genes in Chironomus tentans (Diptera, chironomidae) larvae exposed to various environmental pollutants: a potential biomarker of freshwater monitoring

Chemosphere
Soon-Mi LeeJinhee Choi

Abstract

To identify a sensitive biomarker of freshwater monitoring, we evaluated pollutant-induced expression of heat shock proteins (HSPs) and hemoglobins (Hbs) genes in the larvae of the aquatic midge Chironomus tentans (Diptera, Chironomidae). As pollutants, we examined nonylphenol, bisphenol-A, 17alpha-ethynyl estradiol, bis(2-ethylhexyl) phthalate, endosulfan, paraquat dichloride, chloropyriphos, fenitrothion, cadmium chloride, lead nitrate, potassium dichromate, benzo[a]pyrene and carbon tetrachloride. We also investigated larval growth as a physiological descriptor by measuring changes in the body fresh weight and dry weight after chemical exposure. The response of the HSPs gene expression by chemical exposure was rapid and sensitive to low chemical concentrations but it was not stressor specific. Interestingly, an increase in the expression of HSPs genes was observed not only in a stress inducible form (HSP70), but also in a constitutively (HSC70) expressed form. The expression of Hb genes showed chemical-specific responses: that is, alkyl phenolic compounds increased the expression of hemoglobin genes, whereas pesticides decreased the expression. As expected, molecular-level markers were more sensitive than physiological endpo...Continue Reading

References

Feb 22, 2002·Journal of Biochemical and Molecular Toxicology·Tatsuya YoshimiTakashi Miura
Jul 23, 2003·The Science of the Total Environment·Natalie K Karouna-Renier, Jonathan P Zehr
Jul 31, 2003·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Jeanette M Rotchell, Gary K Ostrander
Sep 1, 1994·Ecotoxicology·D B Peakall, C H Walker

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Citations

Sep 4, 2008·Cell and Tissue Research·Kristina HolmMichael Thorndyke
May 18, 2013·Journal of Environmental Management·S MagdouliR D Tyagi
Jun 17, 2009·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jörg OehlmannCharles R Tyler
Mar 8, 2014·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Katherine J JeppeAry A Hoffmann
Aug 12, 2015·Aquatic Toxicology·Neil FullerAlex T Ford
May 23, 2012·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Kiyun Park, Inn-Sil Kwak
Apr 9, 2011·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Prakash M Gopalakrishnan Nair, Jinhee Choi
Oct 23, 2010·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Mónica MoralesGloria Morcillo
Sep 28, 2010·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Yinghua ShuJianwu Wang
Jun 24, 2010·Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics·Amit Kumar SinhaJohan Robbens
Feb 9, 2010·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Kiyun ParkInn-Sil Kwak
Jan 12, 2010·Life Sciences·Subash C GuptaDebapratim K Chowdhuri
Oct 31, 2009·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Anne Vatland KrøvelPål A Olsvik
Jun 6, 2009·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Kiyun Park, Inn-Sil Kwak
Sep 1, 2009·Environmental Toxicology and Pharmacology·Tatsuya YoshimiTakashi Miura
May 1, 2009·Ecotoxicology and Environmental Safety·Reyna Colli-DuláOmar Zapata-Perez
Aug 30, 2008·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Jae-Sung RheeJae-Seong Lee
Sep 3, 2008·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Kiyun Park, Inn-Sil Kwak
May 6, 2008·Ecotoxicology and Environmental Safety·Dorthe JensenMartin Holmstrup

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