PMID: 9535122Apr 16, 1998Paper

Expression of Kin, a nuclear protein binding to curved DNA, in mammal and avian brains

Neuroscience Letters
N MermetS Araneda

Abstract

Kin is a nuclear protein which presents cross-immunoreactivity with the bacterial RecA protein and which efficiently binds to curved DNA. This genomic interaction could be implied in DNA repair and illegitimate recombination in eukaryotic cells. Using immunocytochemistry with anti-RecA antibodies, we report the ubiquitous presence of the Kin protein in the CNS of mice and quails. However, some brain structures such as the hippocampal area, the locus coeruleus and Purkinje cells are preferentially immunolabelled and show some homologies between the two species. In conclusion, the expression of the Kin protein is preserved in the phylogeny of the brain of higher vertebrates.

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Citations

Mar 7, 2002·The Journal of Biological Chemistry·Denis S F BiardJaime F Angulo
Jun 11, 2008·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Shan-Zheng YangFeng-Yan Sun

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