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Expression of LAG-3 is coincident with the impaired effector function of HBV-specific CD8(+) T cell in HCC patients

Immunology Letters

Dec 25, 2012

Fu-Jun LiDe-Quan Wu

Abstract

Hepatitis B virus (HBV)-specific T cells play a key role in the pathogenesis of hepatocellular carcinoma (HCC), but little is known about the regulation of HBV-specific CD8(+) T cells function in HCC patients. Lymphocyte activation gene-3 (LAG-3) is an inhibitory molecule with diverse b...read more

Mentioned in this Paper

Tumor Virus Infections
Establishment and Maintenance of Localization
Pathogenic Aspects
T-Lymphocyte
Leukocyte Differentiation Antigens, Human
Peripheral Blood
Lymphocytes as Percentage of Blood Leukocytes (Lab Test)
Hepatitis
Hepatitis Delta Virus
Amino Acids, I.V. solution additive
Paper Details
References
  • References23
  • Citations25
123
  • References23
  • Citations25
123

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Expression of LAG-3 is coincident with the impaired effector function of HBV-specific CD8(+) T cell in HCC patients

Immunology Letters

Dec 25, 2012

Fu-Jun LiDe-Quan Wu

PMID: 23261718

DOI: 10.1016/j.imlet.2012.12.004

Abstract

Hepatitis B virus (HBV)-specific T cells play a key role in the pathogenesis of hepatocellular carcinoma (HCC), but little is known about the regulation of HBV-specific CD8(+) T cells function in HCC patients. Lymphocyte activation gene-3 (LAG-3) is an inhibitory molecule with diverse b...read more

Mentioned in this Paper

Tumor Virus Infections
Establishment and Maintenance of Localization
Pathogenic Aspects
T-Lymphocyte
Leukocyte Differentiation Antigens, Human
Peripheral Blood
Lymphocytes as Percentage of Blood Leukocytes (Lab Test)
Hepatitis
Hepatitis Delta Virus
Amino Acids, I.V. solution additive

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References23
  • Citations25
123
  • References23
  • Citations25
123
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