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Expression of neuron-associated tumor necrosis factor alpha in the brain is increased during persistent pain

Regional Anesthesia and Pain Medicine

Jul 20, 2002

William C CoveyRobert Nicholas Spengler

PMID: 12132059

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Abstract

Evidence implicates the pleiotropic cytokine tumor necrosis factor alpha (TNFalpha) in the pathogenesis of persistent pain. The present study employs a chronic constriction injury (CCI) model of neuropathic pain to examine TNFalpha production in the central nervous system (CNS) and in t...read more

Mentioned in this Paper

Brain
Brain Stem
Chronic Disease
Hyperalgesia
Laboratory Procedures
Structure of Locus Ceruleus
Neck
Necrosis
Neuralgia
Neurons
Paper Details
References
  • References22
  • Citations35
123
  • References22
  • Citations35
1234

Expression of neuron-associated tumor necrosis factor alpha in the brain is increased during persistent pain

Regional Anesthesia and Pain Medicine

Jul 20, 2002

William C CoveyRobert Nicholas Spengler

PMID: 12132059

DOI:

Abstract

Evidence implicates the pleiotropic cytokine tumor necrosis factor alpha (TNFalpha) in the pathogenesis of persistent pain. The present study employs a chronic constriction injury (CCI) model of neuropathic pain to examine TNFalpha production in the central nervous system (CNS) and in t...read more

Mentioned in this Paper

Brain
Brain Stem
Chronic Disease
Hyperalgesia
Laboratory Procedures

Related Papers

Paper Details
References
  • References22
  • Citations35
123
  • References22
  • Citations35
1234

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