Jan 1, 1979

Expression of T-antigen on polyagglutinable erythrocytes and carcinoma cells: preparation of T-activated erythrocytes, anti-T lectin, anti-T absorbed human serum and purified anti-T antibody

Vox Sanguinis
D R Howard

Abstract

Recent interest has been revived in the human MN blood group system due to the discovery of the MN precursor substance (T-antigen) on certain malignant, but not benign or normal tissues. Methods for preparing T-activated erythrocytes, anti-T lectin, anti-T absorbed human serum and purified anti-T antibody are described and should be useful not only to the researcher involved in this new line of investigation, but also to the routine blood bank faced with the occasional problem of erythrocyte polyagglitinability.

Mentioned in this Paper

Viral Tumor Antigens
Blood Group H Type 1 Antigen
Hemagglutination
Process of Absorption
Neuraminidase
Biologic Preservation
Malignant Paraganglionic Neoplasm
Lectin Activity
Specimen Type - Erythrocytes
Red Blood Cell Count Measurement

About this Paper

Related Feeds

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.