PMID: 2105081Jan 1, 1990Paper

Expression of the yeast LEU4 gene is subject to four different modes of control

Archives of Biochemistry and Biophysics
M H PetersG B Kohlhaw

Abstract

A translational fusion of yeast LEU4 and Escherichia coli lacZ which contains 679 bp of the LEU4 5'-flanking region and the first two codons of LEU4 was used to study LEU4 expression. Eight recipient strains with different genetic backgrounds, transformed with a plasmid containing the fusion, were grown under a variety of conditions, and beta-galactosidase activity was measured. Evidence was obtained for at least four modes of expression of LEU4: general amino acid control, leucine-specific control, basal level expression, and branched-chain amino acid-mediated repression. Determination of steady-state levels of LEU4 mRNA suggested that LEU4 expression is regulated transcriptionally.

References

Dec 21, 1984·Nucleic Acids Research·W KramerH J Fritz
Jan 1, 1983·Journal of Bacteriology·H ItoA Kimura
Jan 1, 1983·Annual Review of Microbiology·N Gunge
Jul 1, 1981·Molecular and Cellular Biology·P NiederbergerR Hütter

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Citations

Mar 11, 2003·Microbiology and Molecular Biology Reviews : MMBR·Gunter B Kohlhaw
Jul 27, 2010·PloS One·Erica M Larson, Alexander Idnurm
Mar 10, 1995·The Journal of Biological Chemistry·Y Hu, G B Kohlhaw
Jun 1, 1994·Current Genetics·A Gedvilaite, K Sasnauskas

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