PMID: 9555074May 16, 1998Paper

Expression pattern of a novel death-promoting gene, DP5, in the developing murine nervous system

Brain Research. Molecular Brain Research
K KanazawaA Wanaka

Abstract

We examined the expression patterns of the DP5 gene, which encodes a protein with apoptosis-inducing activity, in the developing nervous system of mice. This gene was primarily expressed in the spinal motor neurons and peripheral sensory ganglia of mouse embryos and transiently in the postnatal brain, particularly in the entorhinal cortex and hippocampus. These expression patterns suggest that the DP5 gene may be involved in the apoptosis, if not all, of the developing nervous system.

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Citations

Feb 14, 2002·Neuroscience Letters·Taketoshi WakabayashiSachiko Hommura
Oct 29, 2010·The Journal of Biological Chemistry·Fabrice MooreDecio L Eizirik
Mar 5, 2004·Biochimica Et Biophysica Acta·Rizwan S AkhtarKevin A Roth
Jun 24, 2019·The FEBS Journal·Emilie HollvilleMohanish Deshmukh

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Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis