PMID: 11900978Mar 20, 2002Paper

Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development

Mechanisms of Development
M K Hajihosseini, John K Heath

Abstract

The normal development of calvarial bones and sutures critically relies on proper signalling through Fgf receptors, but the source and identity of cognate ligands have remained unknown. Reverse transcriptase polymerase chain reaction analysis in this study shows that a broad range of Fgf ligands are expressed in the coronal sutures separating the parietal and frontal bones. Analysis by whole mount in situ hybridization further reveals distinct expression patterns for Fgf-18, Fgf-20, and by comparison, Fgf-9, in the calvaria, and Fgfs-20 and -9 in the developing limbs, suggestive of their role in proliferation, differentiation and apoptosis.

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Citations

Mar 23, 2013·Disease Models & Mechanisms·Neus Martínez-AbadíasJoan T Richtsmeier
Aug 26, 2014·Database : the Journal of Biological Databases and Curation·Michaela MatthesDietrich Trümbach
Dec 22, 2015·Seminars in Cell & Developmental Biology·Shahida Moosa, Bernd Wollnik
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Oct 16, 2004·The EMBO Journal·Mitsuaki FujimotoAkira Nakai
Sep 6, 2008·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Mohammad K HajihosseiniClive Dickson
Dec 10, 2015·Disease Markers·A R RamaJ Prados
Mar 10, 2004·Expert Opinion on Biological Therapy·Mark P MooneyMichael I Siegel
Oct 13, 2007·Osteoarthritis and Cartilage·K JaegerB Mueller-Hilke
Apr 12, 2003·Developmental Cell·C Tickle
May 31, 2011·Biochemical and Biophysical Research Communications·Hajime YamauchiNobuyuki Itoh
Oct 13, 2007·Developmental Biology·Eva Lana-ElolaDavid P C Rice
Mar 11, 2008·Molecular and Cellular Neurosciences·Mohammad K HajihosseiniSaverio Bellusci
Dec 22, 2016·Scientific Reports·Nan JiangJeremy J Mao
Jul 15, 2004·The Journal of Biological Chemistry·Martina I ReinholdMichael C Naski
Nov 25, 2005·The Journal of Biological Chemistry·Eiichi TakakiAkira Nakai
Oct 13, 2020·Journal of Zhejiang University. Science. B·Guo-Hao Lin, Lan Zhang
Dec 12, 2003·Development·Mohammad K HajihosseiniJohn K Heath
Mar 8, 2005·Gene Expression Patterns : GEP·Sarah CormierCaroline Silve
Sep 20, 2006·Neuro-Chirurgie·H Khonsari, M Catala

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Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis