Expression patterns of tight junction proteins in porcine major salivary glands: a comparison study with human and murine glands

Journal of Anatomy
Xue-Ming ZhangYan Zhang

Abstract

Tight junction (TJ) proteins play a dynamic role in paracellular fluid transport in salivary gland epithelia. Most TJ studies are carried out in mice and rats. However, the morphology of rodent salivary glands differs from that of human glands. This study aimed to compare the histological features and the expression pattern of TJ proteins in porcine salivary glands with those of human and mouse. The results showed that porcine parotid glands were pure serous glands. Submandibular glands (SMGs) were serous acinar cell-predominated mixed glands, whereas sublingual glands were mucous acinar cell-predominated. Human SMGs were mixed glands containing fewer mucous cells than porcine SMGs, whereas the acinar cells of murine SMGs are seromucous. The histological features of the duct system in the porcine and human SMGs were similar and included intercalated, striated and excretory ducts, but the murine SMG contained a specific structure, the granular convoluted tubule. TJ proteins, including claudin-1 to claudin-12, occludin and zonula occludin-1 (ZO-1), were detected in the porcine major salivary glands and human SMGs by RT-PCR; however, claudin-6, claudin-9 and claudin-11 were not detected in the murine SMG. As shown by immunofluores...Continue Reading

References

Feb 1, 1968·Archives of Oral Biology·S DreizenB M Levy
Nov 15, 2002·Journal of Cell Science·Salah AmashehMichael Fromm
Jul 1, 1962·The American Journal of Anatomy·J M SHACKLEFORD, E C KLAPPER
Sep 15, 2004·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Atsushi HashizumeYohki Hieda
Apr 12, 2005·Advanced Drug Delivery Reviews·Jun Miyoshi, Yoshimi Takai
Jul 21, 2005·International Journal of Radiation Oncology, Biology, Physics·Jun LiSonglin Wang
Jun 7, 2007·Histochemistry and Cell Biology·Jan Ole KriegsRolf K H Kinne
Jan 19, 2008·Biochimica Et Biophysica Acta·Jun Miyoshi, Yoshimi Takai
Sep 4, 2008·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Ola M MariaSimon D Tran
Jun 29, 2010·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Jian ZhouSonglin Wang
Jul 9, 2010·Experimental Physiology·UNKNOWN NC3Rs Reporting Guidelines Working Group
Feb 1, 2011·FEBS Letters·Katsuhiko MinetaSachiko Tsukita
Sep 13, 2014·European Journal of Oral Sciences·Liang ShiFeng-Cai Wei
Sep 25, 2014·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Rachel E MellasOlga J Baker
Jan 23, 2015·Tissue Barriers·Halim KhairallahIndra R Gupta
Oct 16, 2015·Journal of Dental Research·J LiG Y Yu
Mar 5, 2016·Journal of Dental Research·L W ZhangL L Wu
Apr 12, 2016·Scientific Reports·Ching-Shuen WangOlga J Baker
Apr 30, 2016·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Kihoon NamOlga J Baker
Sep 11, 2016·Materials Science & Engineering. C, Materials for Biological Applications·R HedayatiA A Zadpoor

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved