Expression profile of adiponectin and adiponectin receptors in high-fat diet feeding chickens

Journal of Animal Physiology and Animal Nutrition
Ching-Yi ChenYuan-Yu Lin

Abstract

Adiponectin is a circulatory cytokine secreted from adipose tissues and exerts critical metabolic functions in mammals. However, expression profiles of adiponectin and adiponectin receptors in the avian species that may be very different from mammals, especially under affluent nutrition conditions, remain unexplored to examine the effects of adiponectin and adiponectin receptors in chicken adipose tissues under high-fat diet (HFD) feeding. Twenty Taiwan country chickens (L2 bred) of 12 weeks old were challenged with a 10% high-fat diet for 6 weeks. Results showed that body weights and plasma triglycerides, cholesterol and dipeptidyl peptidase-4 (DPP4) were all increased in the HFD treatments. Interestingly, we first demonstrated that chicken circulating macromolecule adiponectin and fat disulphide-bond A oxidoreductase-like protein (DsbA-L), a regulator involved in adiponectin secretion, were elevated upon HFD feeding. Moreover, the mRNA expression of adiponectin and adiponectin receptors as well as additional adipose-related genes such as fatty acid synthase (FAS), adipose triglyceride lipase (ATGL), lipoprotein lipase (LPL), and peroxisome proliferator-activated receptor γ (PPARγ) were also increased in the chicken abdominal ...Continue Reading

References

Nov 10, 1995·The Journal of Biological Chemistry·P E SchererH F Lodish
Apr 16, 1996·Biochemical and Biophysical Research Communications·K MaedaK Matsubara
May 3, 1996·The Journal of Biological Chemistry·E HuB M Spiegelman
Aug 2, 2001·Nature Medicine·A H BergP E Scherer
Jun 13, 2003·Nature·Toshimasa YamauchiTakashi Kadowaki
May 16, 2006·Domestic Animal Endocrinology·Ramesh RamachandranShana L Metzger
Nov 27, 2007·Nature Clinical Practice. Rheumatology·Francisca LagoOreste Gualillo
Jul 29, 2008·Reproduction : the Official Journal of the Society for the Study of Fertility·Olga M Ocón-GroveRamesh Ramachandran
May 28, 2013·General and Comparative Endocrinology·Ramesh RamachandranJill A Hadley
Jul 31, 2013·Journal of Animal Physiology and Animal Nutrition·J YanC Sun
Aug 1, 2015·Reproductive Biology and Endocrinology : RB&E·Mélodie DiotJoëlle Dupont

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