PMID: 8590282Aug 31, 1995Paper

Expression profiles of a human gene identified as a structural homologue of meiosis-specific recA-like genes

DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes
S SatoS Tabata

Abstract

Using the cDNA clone from mouse testis which carries the conserved sequences among meiosis-specific recA-like genes, a highly homologous cDNA clone was isolated from a cDNA library of human testis. The clone had the coding capacity of a protein consisting of 340 amino acid residues, which coincides with the average size of putative eukaryotic recA-like proteins. When expression of the corresponding gene, named HsLIM15, in various tissues was examined by reverse transcription-PCR, products of two different sizes were detected in testis: While the longer was predominantly seen in the testis, the shorter was commonly to all the tissues including the testis. Analysis of the sequences indicated that the longer product corresponded to the above cDNA clone, and the shorter one was its deletion product missing an internal 165 bp portion. The result strongly suggests that the mRNA species coding for the putative meiosis-specific RecA-like protein in human is predominantly expressed in testis possibly as an alternative splicing product of a ubiquitously expressed gene.

Citations

Jan 8, 2008·Science in China. Series C, Life Sciences·Min TaoYun Liu
Aug 17, 2001·Mutation Research·A PastinkP H Lohman
Sep 21, 2002·Current Opinion in Genetics & Development·Julian P Venables
Oct 13, 1999·Mutation Research·A Pastink, P H Lohman
Jan 12, 2011·Journal of Experimental Botany·Bernd Edlinger, Peter Schlögelhofer
Jun 4, 2011·Genetics and Molecular Biology·Wei ZhangQun Wang
Jan 2, 2008·European Journal of Endocrinology·Béatrice Mandon-PépinMarc Fellous
Jul 8, 1997·Proceedings of the National Academy of Sciences of the United States of America·M C RiceE B Kmiec
Oct 23, 1997·Proceedings of the National Academy of Sciences of the United States of America·Z LiC M Radding
Aug 24, 1999·Gene Therapy·R J Yáñez, A C Porter
Mar 1, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Hiroko Kajiura-KobayashiYoshitaka Nagahama

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