Extended distal pancreatectomy with en bloc resection of the celiac axis for locally advanced pancreatic cancer: a case report and review of the literature.

Case Reports in Medicine
Patrick H AlizaiKarsten Junge

Abstract

Due to a lack of early symptoms, pancreatic cancers of the body and tail are discovered mostly at advanced stages. These locally advanced cancers often involve the celiac axis or the common hepatic artery and are therefore declared unresectable. The extended distal pancreatectomy with en bloc resection of the celiac artery may offer a chance of complete resection. We present the case of a 48-year-old female with pancreatic body cancer invading the celiac axis. The patient underwent laparoscopy to exclude hepatic and peritoneal metastasis. Subsequently, a selective embolization of the common hepatic artery was performed to enlarge arterial flow to the hepatobiliary system and the stomach via the pancreatoduodenal arcades from the superior mesenteric artery. Fifteen days after embolization, the extended distal pancreatectomy with splenectomy and en bloc resection of the celiac axis was carried out. The postoperative course was uneventful, and complete tumor resection was achieved. This case report and a review of the literature show the feasibility and safety of the extended distal pancreatectomy with en bloc resection of the celiac axis. A preoperative embolization of the celiac axis may avoid ischemia-related complications of t...Continue Reading

References

Aug 1, 1996·The British Journal of Surgery·J M FabreH Baumel
Dec 1, 1996·Gastrointestinal Endoscopy·M J Wiersema, L M Wiersema
Mar 1, 1997·Surgical Endoscopy·M CaratozzoloL Angelini
Apr 1, 1997·Gastrointestinal Endoscopy Clinics of North America·N HaradaL M Wiersema
Jul 1, 1997·Journal of Surgical Oncology·T TakahashiH Katoh
Aug 1, 1997·International Journal of Pancreatology : Official Journal of the International Association of Pancreatology·T MayumiN Hayakawa
Apr 4, 1998·The Annals of Thoracic Surgery·F Le Pimpec BarthesR Jancovici
May 11, 1999·Annals of Surgery·K D LillemoeC J Yeo
Sep 11, 1999·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·R J BoldD B Evans
Nov 24, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Z ZhuM W Büchler
Apr 18, 2001·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·T A SohnK D Lillemoe
Mar 31, 2004·Surgery Today·Satoshi KondoShunichi Okushiba
Aug 17, 2004·Digestive Surgery·Jürgen WeitzMarkus W Büchler
Oct 21, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D StefanidisC R Thomas
Mar 22, 2006·Best Practice & Research. Clinical Gastroenterology·Yu Jo Chua, David Cunningham
Aug 22, 2006·American Journal of Surgery·Singh GagandeepRick Selby
Oct 1, 2008·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·A M ChromikW Uhl
Jan 13, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Sascha A MüllerMarkus W Büchler
Sep 28, 2010·The Annals of Thoracic Surgery·Marc BludauWolfgang Schröder
Oct 12, 2010·Cardiovascular and Interventional Radiology·Timm DeneckeMatthias Glanemann

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Methods Mentioned

BETA
pancreatectomy
dissection

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