PMID: 8957356Dec 1, 1996Paper

Extended indications for lung volume reduction surgery in advanced emphysema

The Annals of Thoracic Surgery
M ArgenzianoM E Ginsburg

Abstract

Lung volume reduction surgery has shown early promise as a palliative therapy in severe emphysema. Selection of potential candidates has been based on certain functional and anatomic criteria, and a variety of operative contraindications have been proposed. Over 15 months, we performed lung volume reduction surgery in 85 patients selected on the basis of severe hyperinflation with air trapping, diaphragmatic dysfunction, and disease heterogeneity. Patients were not excluded on the basis of severe hypercapnia, steroid dependence, profound pulmonary dysfunction, or inability to complete preoperative rehabilitation. We observed significant improvements in pulmonary function, exercise capacity, and dyspnea, with an acceptable 30-day perioperative mortality of 7% and actuarial survival of 90% and 83% at 6 and 12 months, respectively. In each "high-risk" group, perioperative mortality, actuarial survival to 1 year, and functional results were equivalent, and in some cases superior, to those in the corresponding "low-risk" patients. Severe hypercapnia, steroid dependence, profound pulmonary dysfunction, and inability to complete preoperative rehabilitation do not preclude successful lung volume reduction surgery and should not be rega...Continue Reading

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Citations

Sep 13, 2001·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·K MitsuiS Satomi
Jan 15, 2004·American Journal of Respiratory Medicine : Drugs, Devices, and Other Interventions·Francis C Cordova, Gerard J Criner
Aug 1, 1996·The Annals of Thoracic Surgery·K S Naunheim, M K Ferguson
Mar 6, 2004·The Journal of Thoracic and Cardiovascular Surgery·Bryan F MeyersJoel D Cooper
Mar 1, 1997·The Annals of Thoracic Surgery·W WisserW Klepetko
Aug 1, 1997·The Annals of Thoracic Surgery·M ArgenzianoL A Gorenstein
Oct 13, 2001·The New England Journal of Medicine·UNKNOWN National Emphysema Treatment Trial Research GroupRobert Wise
Jan 23, 1998·Journal of Internal Medicine·G Hillerdal
May 29, 1998·American Journal of Respiratory and Critical Care Medicine·M D BeckerM E Ginsburg
Apr 8, 1999·American Journal of Respiratory and Critical Care Medicine·H E Fessler, R A Wise
Oct 13, 2000·American Journal of Respiratory and Critical Care Medicine·W ChatilaG J Criner
Jul 2, 2011·American Journal of Respiratory and Critical Care Medicine·Gerard J CrinerFernando J Martinez
May 6, 2008·Proceedings of the American Thoracic Society·Gerard J CrinerUNKNOWN National Emphysema Treatment Trial Research Group
Nov 20, 1997·AORN Journal·G M Allen, J J DeRose
Nov 1, 2016·Interactive Cardiovascular and Thoracic Surgery·Priyadharshanan AriyaratnamNilanjan Chaudhuri
Apr 30, 2004·The Journal of Thoracic and Cardiovascular Surgery·Robert J McKennaUNKNOWN National Emphysema Treatment Trial Research Group
Jun 1, 1997·Clinics in Chest Medicine·R D YusenE P Trulock
Dec 14, 1999·The Journal of Thoracic and Cardiovascular Surgery·D L SernaA F Wilson
Jun 11, 1998·Mayo Clinic Proceedings·J P UtzC Deschamps
Oct 4, 2006·Current Opinion in Anaesthesiology·B Mets
Oct 6, 2006·Current Opinion in Anaesthesiology·Edmond Cohen
Nov 11, 2005·Clinical Trials : Journal of the Society for Clinical Trials·Shing M LeeUNKNOWN National Emphysema Treatment Trial Research Group
Jun 17, 2000·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·K S NaunheimC A Keller
Jun 17, 2000·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·W WisserW Klepetko
Aug 3, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Ali AkilStefan Fischer
Oct 1, 1998·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·W WisserE Wolner
Mar 4, 1998·The Annals of Thoracic Surgery·J J DeRoseM E Ginsburg
Feb 24, 2001·Clinics in Chest Medicine·K R Flaherty, F J Martinez

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