Extended loci histocompatibility matching in HSCT-Going beyond classical HLA.

International Journal of Immunogenetics
Christine NeuchelJoannis Mytilineos

Abstract

Unrelated haematopoietic stem cell transplantation (HSCT) has evolved from an experimental protocol to a potentially curative first-line treatment in a variety of haematologic malignancies. The continuous refinement of treatment protocols and supportive care paired with ongoing achievements in the technological field of histocompatibility testing enabled this transformation. Without a doubt, HLA matching is still the foremost criterion for donor selection in unrelated HSCT. However, HSCT-related treatment complications still occur frequently, often resulting in patients suffering severely or even dying as a consequence of such complications. Current literature indicates that other immune system modulating factors may play a role in the setting of HSCT. In this review, we discuss the current clinical evidence of a possible influence of nonclassical HLA antigens HLA-E, HLA-F, and HLA-G as well as the HLA-like molecules MICA and MICB, in HSCT.

References

May 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·A Ishitani, D E Geraghty
Jan 1, 1990·Immunologic Research·H Heinrichs, H T Orr
Jul 5, 1994·Proceedings of the National Academy of Sciences of the United States of America·S BahramT Spies
Dec 1, 1993·Human Molecular Genetics·G A HarrisonD W Cooper
Oct 29, 1996·Proceedings of the National Academy of Sciences of the United States of America·V GrohT Spies
Jan 1, 1997·Human Immunology·C Grimsley, C Ober
Feb 18, 1997·Proceedings of the National Academy of Sciences of the United States of America·N MizukiH Inoko
Mar 5, 1998·Nature·V M BraudA J McMichael
Oct 28, 1998·Trends in Cell Biology·B Martoglio, B Dobberstein
Apr 6, 1999·The Journal of Experimental Medicine·S Rajagopalan, E O Long
Jun 9, 1999·Proceedings of the National Academy of Sciences of the United States of America·V GrohT Spies
Jun 17, 1999·Immunogenetics·E W PetersdorfJ A Hansen
Dec 22, 1999·The Journal of Immunology : Official Journal of the American Association of Immunologists·S D WainwrightC H Holmes
Oct 18, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·D SaverinoE Ciccone
Feb 13, 2001·European Journal of Immunology·E J LepinC A O'Callaghan
Mar 30, 2001·Molecular Human Reproduction·K A PfeifferK van der Ven
Jun 8, 2001·Human Immunology·Y ZhangP Stastny
Jun 29, 2001·Trends in Immunology·H A Stephens
Aug 8, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·S RajagopalanE O Long
Nov 24, 2001·Molecular Human Reproduction·C L AldrichC Ober
Mar 29, 2002·European Journal of Immunology·Pilar GarcíaMiguel López-Botet
May 29, 2002·Proceedings of the National Academy of Sciences of the United States of America·Eddie C Y WangGavin W G Wilkinson
Feb 6, 2003·International Journal of Cancer. Journal International Du Cancer·Masahisa JinushiNorio Hayashi
May 13, 2003·Nature Immunology·Daniel D BilladeauPaul J Leibson
Jul 11, 2003·Proceedings of the National Academy of Sciences of the United States of America·Mitsunori ShiroishiKatsumi Maenaka
Sep 23, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Akiko Kikuchi-MakiKerry S Campbell
Oct 22, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Jason L PetersenJoyce C Solheim
Nov 7, 2003·Human Immunology·Vera RebmannHans Grosse-Wilde

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Related Papers

[Rinshō ketsueki] The Japanese journal of clinical hematology
Makoto Onizuka
Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur̈ Transfusionsmedizin Und Immunham̈atologie
Daniel FürstJoannis Mytilineos
The Medical Journal of Malaysia
N T Rafeah, S A W Fadilah
Transfusion clinique et biologique : journal de la Société française de transfusion sanguine
Dominique Charron
© 2021 Meta ULC. All rights reserved