PMID: 9179270May 1, 1997Paper

Extended lymph node dissection in gastrointestinal cancer

Journal of Surgical Oncology
M Noguchi, I Miyazaki

Abstract

We reviewed the literature concerning the effect of extended lymph node dissection on survival in patients with gastrointestinal cancer. Most retrospective and/or prospective nonrandomized comparative studies have claimed that extended lymph node dissection significantly improves survival rate in patients with esophageal cancer, gastric cancer, and colorectal cancer. However, it is difficult to interpret these results since specialized care provided in trials may itself improve survival. In gastric cancer, several prospective randomized trials have failed to demonstrate a survival advantage of extended dissection, while there are few well-done prospective randomized trials in esophageal or colorectal cancer. Therefore, the therapeutic value of extended lymph node dissection remains to be determined in gastrointestinal cancer. Randomized prospective studies within the bounds of the ethical treatment of patients can and should be done.

References

Sep 1, 1976·The British Journal of Surgery·H E Lockhart-MummeryP R Hawley
Apr 1, 1992·The Surgical Clinics of North America·K E BehrnsM G Sarr
Mar 1, 1991·The British Journal of Surgery·P GunvénT Kinoshita
Jun 1, 1991·The Annals of Thoracic Surgery·H KatoT Iizuka
Jun 1, 1990·The British Journal of Surgery·P SurteesR K Phillips
Oct 1, 1986·Annals of Surgery·D B SkinnerV M Staszak
Feb 1, 1988·The British Journal of Surgery·T T Irvin, J E Bridger
Feb 1, 1988·The British Journal of Surgery·D M DentS K Price
Aug 1, 1988·Archives of Surgery·B E Bodner
Aug 1, 1987·World Journal of Surgery·J Jeekel
Sep 1, 1987·The British Journal of Surgery·X de AretxabalaI Miyazaki
Mar 1, 1986·The Annals of Thoracic Surgery·D M ShahianE Watkins
Mar 1, 1972·The Japanese Journal of Surgery·S MajimaT Takahashi
Dec 6, 1969·British Medical Journal·J M Edwards, J B Kinmonth
Sep 1, 1969·The British Journal of Surgery·J M Edwards, J B Kinmonth
Feb 1, 1984·Cancer·W L Donegan
Sep 1, 1984·The Japanese Journal of Surgery·K Inokuchi
Mar 1, 1981·World Journal of Surgery·Y KodamaK Inokuchi
Jan 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A M BuntJ A Bruijn
May 1, 1994·World Journal of Surgery·T P Hennessy
Sep 1, 1994·Annals of Surgery·H AkiyamaY Kajiyama
Oct 1, 1993·The Annals of Thoracic Surgery·W T VigneswaranM S Allen
Mar 1, 1993·The British Journal of Surgery·M GoldmincB Launois
Dec 1, 1995·British Journal of Cancer·K MiwaR Falla
Jan 1, 1995·Scandinavian Journal of Gastroenterology. Supplement·C W TaatH Obertop

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